"SDC3" Related Products

Recombinant Human Syndecan 3, His-tagged

Cat. No.: SDC3-504H
Product Overview: Recombinant Human SDC3protein was expressed in Murine myeloma cell line with a C-terminal 6-His tag.Gln48-Lys383.
Description: SDC3, also calledN-syndecan, is one of four vertebrate syndecans that are principal carriersof heparan sulfate and chondroitin sulfate glycosaminoglycans. These type 1transmembrane proteins show conserved cytoplasmic domains and divergentextracellular domains. Human SDC3 is synthesized as a 442 amino acid (aa)core protein with a 44 aa signal sequence, a 343 aa extracellular domain, a21 aa transmembrane region and a 34 aa cytoplasmic tail with a binding sitefor PDZ domains.
Source: Murine myeloma cellline, NS0-derived.
Form: Lyophilized from a0.2 μm filtered solution in PBS.
N-terminalSequence: Gln48 predicted
Molecular Weight: 35.5 kDa
Activity: Measuredby the ability of the immobilized protein to inhibit the adhesion of SAOS2human osteosarcoma cells to human Fibronectin. When 5 x 104 cells/well are added to human SDC3 and human Fibronectin (0.5 μg/mL) coated plates,cell adhesion is blocked in a dose dependent manner after 1 hour at 37°C. TheED50 for this effect is typically 2.5-10 μg/mL.
Endotoxin Level: <1.0 EUper 1 μg of the protein by the LAL method.
SDS-PAGE: 100-150kDa, reducing conditions.
Purity: >85%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: 200 μg/ mLin PBS
Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months fromdate of receipt, -20 to -70°C as supplied. 1 month, 2 to 8 °C under sterileconditions after reconstitution. 3 months, -20 to -70°C under sterileconditions after reconstitution.
Gene Name: SDC3 syndecan 3 [ Homosapiens ]
Official Symbol: SDC3
Synonyms: SDC3; syndecan 3; SDCN;SYND3; syndecan-3; N-syndecan; syndecan neural type; syndecan proteoglycan 3;KIAA0468; OTTHUMP00000040577; syndecan 3 (N-syndecan)
Gene ID: 9672
mRNA Refseq: NM_014654
Protein Refseq: NP_055469
MIM: 186357
UniProt ID: O75056
Chromosome Location: 1pter-p22.3
Pathway: Cell adhesion molecules (CAMs);ECM-receptor interaction; Malaria; Proteogylcan syndecan-mediated signalingevents; Syndecan-3-mediated signaling events
Function: cytoskeletal protein binding

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.