"Fst" Related Products


Recombinant Mouse Follistatin

Cat. No.: Fst-560M
Product Overview: Recombinantmouse Fst protein was expressed in Spodoptera frugiperda, Sf 21 (baculovirus)-derived,with an N-terminus Met. Gly30-Asn317.
Description: Fst was initiallyidentified as a folliclestimulating hormone inhibiting substance found in ovarianfollicular fluid. It has since been shown that Fst is a high-affinity activin-bindingprotein that can act as an activin antagonist. Two alternatively splicedfollistatin mRNAs, encoding mature FS with 288 amino acid (aa) residues (FS-288)and 315 aa residues (FS-315), exist.
Source: Spodopterafrugiperda, Sf 21 (baculovirus)-derived
Form: Lyophilizedfrom a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrierprotein.
N-terminal Sequence: Met
Molecular Weight: 31 kDa
Activity: Measuredby its ability to neutralize Activin-mediated erythroid differentiation of K562human chronic myelogenous leukemia cells. The ED50 for this effectis typically 0.1-0.4 μg/mL in the presence of 7.5 ng/mL rhActivin A.
Endotoxin Level: <1.0 EU per 1 μgof the protein by the LAL method.
SDS-PAGE: 35-40 kDa, reducingconditions
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: Reconstitute at 10μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month,2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions afterreconstitution.
Gene Name: Fst follistatin [ Musmusculus ]
Official Symbol: Fst
Synonyms: Fst; follistatin;AL033346;FS; activin-binding protein
Gene ID: 14313
mRNA Refseq: NM_008046
Protein Refseq: NP_032072
UniProt ID: P47931
Chromosome Location: 13
Pathway: TGF Beta Signaling Pathway
Function: activin binding; binding; heparin sulfateproteoglycan binding

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