"Fzd2" Related Products


Recombinant Mouse Frizzled Homolog 2 (Drosophila), Fc-tagged

Cat. No. : Fzd2-585M
Product Overview : RecombinantMouse Fzd2 protein was expressed in Murine myeloma cell line with the Fc partof Human IgG1 Pro100-Lys330 (C-terminus) and Mouse Frizzled-2 Gln29-Leu168 (N-terminus).
Description : Fzd2 is involved invariety of developmental processes including cell fate determination, cellpolarity, tissue patterning and control of cell proliferation. Members of theFrizzled family of proteins serve as receptors for the Wnt signaling pathway.
Source : Murine myeloma cellline, NS0-derived
Form : Supplied as a 0.2 μmfiltered solution in PBS.
N-terminal Sequence : Gln29 predicted
Molecular Weight : 42.3 kDa
Activity : Measured by itsability to bind biotinylated Wnt-5a in a functional ELISA with an estimated KD< 5 nM.
Endotoxin Level : <1.0 EU per 1 μgof the protein by the LAL method.
SDS-PAGE : 50-55 kDa, reducingconditions
Purity : >90%, by SDS-PAGEunder reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 100μg/mL in sterile PBS.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1month, 2 to 8 °C under sterile conditions after reconstitution.3 months, -20 to-70 °C under sterile conditions after reconstitution.
Gene Name : Fzd2 frizzled homolog 2(Drosophila) [ Mus musculus ]
Official Symbol : Fzd2
Synonyms : Fzd2; frizzledhomolog 2 (Drosophila); Fz10; Fzd10; Mfz10; Mfz10a; AL033370;AW456835; OTTMUSP00000002857; frizzled-2; fz-2;mFz2; fz-10; frizzled-10
Gene ID : 57265
mRNA Refseq : NM_020510
Protein Refseq : NP_065256
UniProt ID : Q9JIP6
Chromosome Location : 11
Pathway : Basal cellcarcinoma; Class B/2 (Secretin family receptors); GPCR ligand binding; HTLV-Iinfection; Melanogenesis; Pathways in cancer; Signal Transduction; Signalingby GPCR; Wnt Signaling Pathway; Wnt signaling network
Function : G-protein coupledreceptor activity; PDZ domain binding; Wnt-activated receptor activity;Wnt-protein binding; protein binding; protein heterodimerization activity;receptor activity; signal transducer activity; transmembrane signalingreceptor activity

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