"Fcrl5" Related Products

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Recombinant Mouse Fc receptor-like 5, His-tagged

Cat. No.: Fcrl5-503M
Product Overview: RecombinantMouse Fcrl5 protein was expressed in Murine myeloma cellline. Met1-Ala496,with a C-terminal 6-His tag.
Description: Fcrl5 is a 90-95kDa member of the FCRL family of proteins whose amino acid (aa) sequence isreminiscent of that for classical Fc receptors. FCLR molecules are type 1transmembrane proteins that contain from 3 to 9 immunoglobulin-like domains.They are differentially expressed within the B cell lineage, and can eitherpromote or inhibit B cell proliferation and activation. Mature mouse Fcrl5 consistsof a 470 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a79 aa cytoplasmic region. The ECD contains five Iglike domains, while the cytoplasmicregion possesses one ITAM-like motif and one immunotyrosine inhibitory motif(ITIM).
Source: Murine myeloma cellline, NS0-derived.
Form: Lyophilized from a0.2 um filtered solution in PBS.
N-terminalSequence: Gln27 predicted
MolecularWeight: 53.5 kDa
Activity: Measuredby its ability to bind mouse IgG with an estimated KD < 400 nM.
Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE: 65-80kDa, reducing conditions.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: Reconstitute at 100μg/mLin PBS.
Storage: Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name: Fcrl5 Fc receptor-like 5 [ Musmusculus ]
Official Symbol: Fcrl5
Synonyms: Fcrl5; Fcreceptor-like 5; Fcrh3; mBXMH2; Fcreceptor-like protein 5; moFcRH3; fcR-like protein 5; BXMAS1-like protein 2;fc receptor homolog 3; Fc receptor-like protein 3
Gene ID: 329693
mRNA Refseq: NM_001113238
Protein Refseq: NP_001106709
UniProt ID: Q68SN8
Chromosome Location: 3
Pathway: T Cell ReceptorSignaling Pathway
Function: molecular_function;receptor activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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