"Fcrl5" Related Products


Recombinant Mouse Fc receptor-like 5, His-tagged

Cat. No. : Fcrl5-503M
Product Overview : RecombinantMouse Fcrl5 protein was expressed in Murine myeloma cellline. Met1-Ala496,with a C-terminal 6-His tag.
Description : Fcrl5 is a 90-95kDa member of the FCRL family of proteins whose amino acid (aa) sequence isreminiscent of that for classical Fc receptors. FCLR molecules are type 1transmembrane proteins that contain from 3 to 9 immunoglobulin-like domains.They are differentially expressed within the B cell lineage, and can eitherpromote or inhibit B cell proliferation and activation. Mature mouse Fcrl5 consistsof a 470 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a79 aa cytoplasmic region. The ECD contains five Iglike domains, while the cytoplasmicregion possesses one ITAM-like motif and one immunotyrosine inhibitory motif(ITIM).
Source : Murine myeloma cellline, NS0-derived.
Form : Lyophilized from a0.2 um filtered solution in PBS.
N-terminalSequence : Gln27 predicted
MolecularWeight : 53.5 kDa
Activity : Measuredby its ability to bind mouse IgG with an estimated KD < 400 nM.
Endotoxin Level : <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE : 65-80kDa, reducing conditions.
Purity : >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 100μg/mLin PBS.
Storage : Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name : Fcrl5 Fc receptor-like 5 [ Musmusculus ]
Official Symbol : Fcrl5
Synonyms : Fcrl5; Fcreceptor-like 5; Fcrh3; mBXMH2; Fcreceptor-like protein 5; moFcRH3; fcR-like protein 5; BXMAS1-like protein 2;fc receptor homolog 3; Fc receptor-like protein 3
Gene ID : 329693
mRNA Refseq : NM_001113238
Protein Refseq : NP_001106709
UniProt ID : Q68SN8
Chromosome Location : 3
Pathway : T Cell ReceptorSignaling Pathway
Function : molecular_function;receptor activity

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