"FCRL5" Related Products


Recombinant Human Fc Receptor-Like 5, His-tagged

Cat. No. : FCRL5-506H
Product Overview : RecombinantHuman FCRL5 protein was expressed in Murine myeloma cellline. Gln16-Arg844,with a C-terminal 6-His tag.
Description : FCRL5 isa 120 kDa protein with sequence homology to classical Fc receptors. They are differentiallyexpressed within the B cell lineage and can either promote or inhibit B cellproliferation and activation. According to R&D Systems testing, FCRL5binds to purified human IgG with high affinity. Mature human FCRL5 consistsof a 836 amino acid (aa) extracellular domain (ECD) with nine Ig-like domains,a 21 aa transmembrane segment, and a 105 aa cytoplasmic domain with one immunotyrosineactivation motif (ITAM) and two immunotyrosine inhibitory motifs (ITIMs).
Source : Murine myeloma cellline, NS0-derived.
Form : Lyophilized from a0.2 um filtered solution in PBS.
N-terminalSequence : Gln16 predicted
MolecularWeight : 91.5 kDa
Activity : Measuredby its ability to bind human IgG with an estimated KD < 30 nM.
Endotoxin Level : <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE : 110-120kDa, reducing conditions.
Purity : >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 100μg/mLin PBS.
Storage : Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name : FCRL5 Fc receptor-like 5 [ Homosapiens ]
Official Symbol : FCRL5
Synonyms : FCRL5;Fc receptor-like 5; Fc receptor-like protein 5; BXMAS1; CD307e; FCRH5; IRTA2;BXMAS1; CD307 antigen; Fc receptor homolog 5; Fc receptor like 5; FcR-likeprotein 5; FCRL5_HUMAN; Immune receptor translocation-associated protein 2;Immunoglobulin receptor translocation associated gene 2 protein;Immunoglobulin superfamily receptor translocation associated gene 2 protein;UNQ503/PRO820; immunoglobulin superfamily receptor translocation associated 2(IRTA2); CD307; PRO820; RP11-217A12.1
Gene ID : 83416
mRNA Refseq : NM_001195388
Protein Refseq : NP_001182317
MIM : 605877
UniProt ID : Q96RD9
Chromosome Location : 1q21
Function : receptor activity

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