"FCRL5" Related Products


Recombinant Human Fc Receptor-Like 5, His-tagged

Cat. No.: FCRL5-506H
Product Overview: RecombinantHuman FCRL5 protein was expressed in Murine myeloma cellline. Gln16-Arg844,with a C-terminal 6-His tag.
Description: FCRL5 isa 120 kDa protein with sequence homology to classical Fc receptors. They are differentiallyexpressed within the B cell lineage and can either promote or inhibit B cellproliferation and activation. According to R&D Systems testing, FCRL5binds to purified human IgG with high affinity. Mature human FCRL5 consistsof a 836 amino acid (aa) extracellular domain (ECD) with nine Ig-like domains,a 21 aa transmembrane segment, and a 105 aa cytoplasmic domain with one immunotyrosineactivation motif (ITAM) and two immunotyrosine inhibitory motifs (ITIMs).
Source: Murine myeloma cellline, NS0-derived.
Form: Lyophilized from a0.2 um filtered solution in PBS.
N-terminalSequence: Gln16 predicted
MolecularWeight: 91.5 kDa
Activity: Measuredby its ability to bind human IgG with an estimated KD < 30 nM.
Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE: 110-120kDa, reducing conditions.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: Reconstitute at 100μg/mLin PBS.
Storage: Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name: FCRL5 Fc receptor-like 5 [ Homosapiens ]
Official Symbol: FCRL5
Synonyms: FCRL5;Fc receptor-like 5; Fc receptor-like protein 5; BXMAS1; CD307e; FCRH5; IRTA2;BXMAS1; CD307 antigen; Fc receptor homolog 5; Fc receptor like 5; FcR-likeprotein 5; FCRL5_HUMAN; Immune receptor translocation-associated protein 2;Immunoglobulin receptor translocation associated gene 2 protein;Immunoglobulin superfamily receptor translocation associated gene 2 protein;UNQ503/PRO820; immunoglobulin superfamily receptor translocation associated 2(IRTA2); CD307; PRO820; RP11-217A12.1
Gene ID: 83416
mRNA Refseq: NM_001195388
Protein Refseq: NP_001182317
MIM: 605877
UniProt ID: Q96RD9
Chromosome Location: 1q21
Function: receptor activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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