"Fcrlb" Related Products

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Recombinant Mouse Fc receptor-like B, His-tagged

Cat. No.: Fcrlb-509M
Product Overview: RecombinantMouse Fcrlb protein was expressed in Murine myeloma cellline. Ala18-Ser427,with a C-terminal 6-His tag.
Description: Fcrlb is a 60kDa protein with sequence homology to classical Fc receptors. There are atleast six type 1 transmembrane FCRL proteins and two that lack transmembranesegments. Each family member contains between three and nine immunoglobulin-likedomains. FCRL proteins are differentially expressed within the B cell lineageand can either promote or inhibit B cell proliferation and activation. Accordingto R&D Systems testing, Fcrlb binds to purifiedmouse IgG. Mouse Fcrlb shares 82% and 94% aa sequence identitywith human and rat Fcrlb, respectively. It contains a putativesignal peptide, three immunoglobulinlik domains, and a mucinlike stalk thatis rich in Pro, Ser, and Thr residues.
Source: Murine myeloma cellline, NS0-derived.
Form: Lyophilized from a0.2 um filtered solution in PBS.
N-terminalSequence: Ala18
MolecularWeight: 46.5 kDa (monomer)
Activity: Measuredby its ability to bind mouse IgG with an estimated KD < 300 nM.
Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE: 60-70kDa, reducing conditions.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: Reconstitute at100μg/mL in PBS.
Storage: Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name: Fcrlb Fc receptor-like B [ Musmusculus ]
Official Symbol: Fcrlb
Synonyms: Fcrlb; Fcreceptor-like B; Fcry; FREB2; FcRL2; FREB-2; Fcrlm2; mFCRL2; Fcreceptor-like B; Fc receptor related Y; fc receptor-like protein 2; Fcreceptor-like mucin-like 2; fc receptor-related protein Y; fc receptor-likeand mucin-like protein 2; fc receptor homolog expressed in B cells protein 2
Gene ID: 435653
mRNA Refseq: NM_001029984
Protein Refseq: NP_001025155
UniProt ID: Q5DRQ8
Chromosome Location: 1
Function: molecular_function

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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