Active Recombinant Human Membrane Metallo-Endopeptidase-Like 1, His-tagged
Cat.No. : | MMEL1-1981H |
Product Overview : | RecombinantHuman MMEL1 protein was expressed in Murine myeloma cellline. Gly69-Trp770,with an N-terminal 6-His tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | MMEL1-1981H |
Description : | MMEL1 is azinc protease of the neprilysin (NEP) family, which also includes NEP, ECE-2,PEX, DINE, Kell and several NEPlike proteins. It is encoded by the MMEL1 genein the human genome and is also known as soluble secreted endopeptidase (SEP),Neprilysinlike 1 and Neprilysin-2. Highly expressed in testis, the cDNApredicted a type II transmembrane protein with a short cytoplasmic tail and alarge ectodomain. Both membranebound and soluble forms were comparable withregard to model substrates, pH optima and inhibitor profiles. The ectodomainof human MMEL1 was expressedwith an N-terminal His tag and purified. |
Source : | Mammalian cells |
Form : | Supplied as a 0.2 μmfiltered solution in Tris, NaCl and ZnCl2. |
N-terminalSequence : | His |
MolecularWeight : | 82 kDa |
Activity : | Measuredby its ability to cleave the fluorogenic peptide substrate, Mca-RPPGFSAFK(Dnp)-OH.The specific activity is > 250 pmoles/min/μg, as measured under thedescribed conditions. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 99 kDa,reducing conditions. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Use amanual defrost freezer and avoid repeated freezethaw cycles. 6 monthsfrom date of receipt, -20 to -70°C as supplied. 3 months,-20to-70°C under sterile conditions after opening. |
Gene Name : | MMEL1 membranemetallo-endopeptidase-like 1 [ Homo sapiens ] |
Official Symbol : | MMEL1 |
Synonyms : | MMEL1; membranemetallo-endopeptidase-like 1; NL1; NL2; SEP; NEP2; MMEL2; NEPII; NEP2 (m);neprilysin-2; neprilysin II; zinc metallopeptidase; soluble secretedendopeptidase; EC 3.4.24.11 |
Gene ID : | 79258 |
mRNA Refseq : | NM_033467 |
Protein Refseq : | NP_258428 |
UniProt ID : | Q495T6 |
Chromosome Location : | 1p36 |
Function : | metal ion binding; metalloendopeptidaseactivity; peptidase activity |
Products Types
◆ Recombinant Protein | ||
MMEL1-3484H | Recombinant Human MMEL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MMEL1-5411H | Recombinant Human MMEL1 Protein, GST-tagged | +Inquiry |
MMEL1-384H | Active Recombinant Human MMEL1, His-tagged | +Inquiry |
◆ Lysates | ||
MMEL1-1121HCL | Recombinant Human MMEL1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket