Active Recombinant Mouse Chemokine (C-X-C motif) Ligand 1

• Cat.No.: Cxcl1-384M
• Product Overview: Recombinantmouse Cxcl1 protein was expressed in E. coli. Arg20-Lys96.

Specification

• Cat. No.: Cxcl1-384M
• Description: Cxcl1 is a smallcytokine belonging to the CXC chemokine family that was previously calledGRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanomagrowth stimulating activity, alpha (MSGA-α).
• Source: E. coli
• Form: Lyophilized from a0.2 μm filtered solution in PBS with BSA as a carrier protein.
• N-terminal Sequence: Arg29
• Molecular Weight: 8 kDa
• Activity: Measured by itsability to induce myeloperoxidase release from cytochalasin B-treated humanneutrophils. The ED50 for this effect is typically 0.3-0.9 μg/mL.Measured by its ability to chemoattract human CXCR2 transfected BaF3 mousepro-B cells. The ED50 for this effect is typically 3-15 ng/mL.
• Endotoxin Level: <1.0 EU per 1 μgof the protein by the LAL method.
• Purity: >97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
• Reconstitution: Reconstitute at 100μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
• Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, -20 to -70°C under sterile conditions after reconstitution. 3 months, -70°Cunder sterile conditions after reconstitution.

Gene Information

• Gene Name: Cxcl1chemokine (C-X-C motif) ligand 1 [ Mus musculus ]
• Official Symbol: Cxcl1
• Synonyms: Cxcl1; chemokine(C-X-C motif) ligand 1; KC; Fsp; N51; gro; Gro1; Mgsa; Scyb1; OTTMUSP00000018305;growth-regulatedalpha protein; KC/GRO-alpha; (KC/GR)-alpha; GRO1 oncogene; secretory proteinN51; C-X-C motif chemokine 1; platelet-derived growth factor-inducibleprotein KC; Hematopoietic synergistic factor;HSF; KC-T
• Gene ID: 14825
• mRNA Refseq: NM_008173
• Protein Refseq: NP_032202
• UniProt ID: P12850
• Chromosome Location: 5
• Pathway: Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-likereceptors); Cytokine-cytokine receptor interaction; Cytokines andInflammatory Response (BioCarta); G alpha (i) signalling events; GPCRdownstream signaling; GPCR ligand binding; Legionellosis; NOD-like receptorsignaling pathway; Peptide ligand-binding receptors; Salmonella infection;Signal Transduction; Signaling by GPCR
• Function: chemokine activity;cytokine activity; growth factor activity