"CCL2" Related Products

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Recombinant Canine Chemokine (C-C motif) Ligand 2

Cat. No.: CCL2-406C
Product Overview: Recombinant Canine CCL2 protein wasexpressed in E. coli. Gln24-Pro101.
Description: Canine CCL2is an 8 kDa member of the CC chemokine family of chemotactic factors. It issynthesized as a 101 amino acid (aa) precursor that contains a 23 aa signalsequence and a 78 aa mature segment. It contains no potential N-linked glycosylationsites and is not known for any posttranslational modifications.
Source: E. coli
Form: Lyophilizedfrom a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
N-terminal Sequence: Noresults obtained: Gln24 predicted
Molecular Weight: 8.8 kDa
Activity: Measured by itsability to chemo-attract human CCR2A transected BaF3 Canine pro-B cells. TheED50 for this effect is typically 0.03-0.15 μg/mL.
Endotoxin Level: <1.0 EU per 1μgof the protein by the LAL method.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: Reconstitute at 25 μg/mL insterile PBS that containing at least 0.1% human or bovine serum albumin.
Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month,2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions afterreconstitution.
Gene Name: CCL2 chemokine (C-C motif)ligand 2 [ Canis lupus familiaris ]
Official Symbol: CCL2
Synonyms: CCL2; chemokine(C-C motif) ligand 2; C-C motif chemokin 2; MCP-1; small-inducible cytokineA2; momocyte chemo attractant protein 1; momocyte chemo attractant protein-1;MCP1; SCYA2
Gene ID: 403981
mRNA Refseq: NM_001003297
Protein Refseq: NP_001003297
UniProt ID: P52203
Chromosome Location: 9
Pathway: Chagasdisease (American trypanosomiasis); Chemokine signaling pathway; Cytokine-cytokinereceptor interaction; Diabetes pathways; Herpes simplex infection;Influenza A; Malaria; NOD-like receptor signaling pathway; PERK regulatedgene expression; Rheumatoid arthritis; Unfolded Protein Response

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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