Active Recombinant Rat Chemokine (C-C motif) Ligand 20
Cat.No. : | Ccl20-409R |
Product Overview : | Recombinantrat Ccl20 protein was expressed in E. coli. Ala26-Met96. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Ccl20-409R |
Description : | Ccl20, also known asMIP3α, LARC (Liver and Activationregulated Chemokine) and as Exodus, is oneof many novel β chemokines identified through bioinformatics. Rat Ccl20 cDNAencodes a 96 amino acid (aa) precursor protein with a 25 aa putative signalpeptide that is predicted to be cleaved to form the 71 aa mature secretedprotein. |
Source : | E. coli |
Form : | Lyophilized from a0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrierprotein. |
N-terminal Sequence : | Ala26 |
Molecular Weight : | 8.2 kDa |
Activity : | Measured by itsability to chemoattract human CCR6 transfected BaF3 mouse pro-B cells. The ED50for this effect is typically 0.5-3 μg/mL. |
Endotoxin Level : | <1.0 EU per 1 μgof the protein by the LAL method. |
Purity : | >97%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstitute at 200μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin. |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month,2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions afterreconstitution. |
Gene Name : | Ccl20 chemokine (C-C motif)ligand 20 [ Rattus norvegicus ] |
Official Symbol : | Ccl20 |
Synonyms : | Ccl20; chemokine(C-C motif) ligand 20; ST38; Scya20; MIP-3-alpha; CCchemokine LARC; CC chemokine ST38; beta chemokine exodus-1; small-induciblecytokine A20; macrophage inflammatory protein 3 alpha; liver andactivation-regulated chemokine; beta-chemokine exodus-1; small induciblecytokine subfamily A20; C-C motif chemokine 20 |
Gene ID : | 29538 |
mRNA Refseq : | NM_019233 |
Protein Refseq : | NP_062106 |
UniProt ID : | P97884 |
Chromosome Location : | 9q34 |
Pathway : | Chemokine receptors bind chemokines; Chemokinesignaling pathway; Class A/1 (Rhodopsin-like receptors); Cytokine-cytokinereceptor interaction; G alpha (i) signalling events; GPCR downstreamsignaling; GPCR ligand binding; Peptide ligand-binding receptors; Rheumatoidarthritis; Signal Transduction; Signaling by GPCR |
Function : | chemokine activity; cytokine activity |
Products Types
◆ Recombinant Protein | ||
CCL20-0624H | Recombinant Human CCL20 Protein, GST-Tagged | +Inquiry |
CCL20-22H | Active Recombinant Human CCL20 Protein | +Inquiry |
Ccl20-2888R | Recombinant Rat Ccl20 Protein | +Inquiry |
CCL20-516H | Active Recombinant Human CCL20 Protein, MIgG2a Fc-tagged | +Inquiry |
CCL20-641H | Recombinant Human CCL20 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
CCL20-447MCL | Recombinant Mouse CCL20 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCCL20 influences dendritic cell migration and differentiation, crucial for initiating immune responses.
CCL20 contributes to cancer progression by shaping the tumor microenvironment and aiding tumor cell invasion.
CCL20 plays a significant role in autoimmune diseases by attracting inflammatory cells to affected joints.
CCL20 is involved in wound healing and tissue repair, facilitating immune cell migration and tissue regeneration.
Changes in CCL20 expression impact skin health, potentially contributing to the development of skin disorders.
CCL20 recruits and activates immune cells to sites of inflammation, coordinating the immune response.
CCL20 impacts mucosal immunity, playing a critical role in immune defense in the gut and respiratory system.
Customer Reviews (3)
Write a reviewExpert protein engineering support, essential for our projects' progress.
Consistent western blot results, an indispensable tool in our lab.
Dependable protein quantification, ensures data precision in our work.
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