"Ccl21a" Related Products

Recombinant Mouse Chemokine (C-C motif) Ligand 21A (serine)

Cat. No. : Ccl21a-412M
Product Overview : Recombinantmouse Ccl21a protein was expressed in E. coli. Ser24-Gly133.
Description : Mouse Ccl21a cDNAencodes a 133 amino acid residue protein with a 23 residue signal peptide thatis cleaved to generate the 110 residue mature protein. Human and mouse Ccl21aare highly conserved, exhibiting 86% amino acid sequence identity. Ccl21a isconstitutively expressed at high levels in lymphoid tissues such as lymphnodes, spleen and appendix.
Source : E. coli
Form : Lyophilized from a0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrierprotein.
N-terminal Sequence : Ser24
Molecular Weight : 12 kDa
Activity : Measured by itsability to chemoattract 5-10 day cultured human peripheral blood lymphocytes(PBL). The ED50 for this effect is typically 50-200 ng/mL. Measuredby its ability to chemoattract human CCR7 transfected BaF3 mouse pro-B cells.The ED50 for this effect is typically 3-15 ng/mL.
Endotoxin Level : <1.0 EU per 1 μgof the protein by the LAL method.
Purity : >97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 10μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month,2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions afterreconstitution.
Gene Name : Ccl21a chemokine (C-C motif)ligand 21A (serine) [ Mus musculus ]
Official Symbol : Ccl21a
Synonyms : Ccl21a;chemokine (C-C motif) ligand 21A (serine); ALP; SLC; plt; CKb9;Tca4; 6Ckine; Scya21; 6CKBAC2; SCYA21a; Scya21b; AW987545; OTTMUSP00000006949;Exodus-2; C-C motif chemokine 21a;CCL21-Ser; CC chemokine 6Ckine-ser; beta chemokineexodus-2; beta-chemokine exodus-2; smallinducible cytokine A21a; small-inducible cytokine A21a; thymus-derivedchemotactic agent 4; TCA4
Gene ID : 18829
mRNA Refseq : NM_011124
Protein Refseq : NP_035254
UniProt ID : P844444
Chromosome Location : 4
Pathway : Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-likereceptors); Cytokine-cytokine receptor interaction; G alpha (i) signallingevents; GPCR downstream signaling; GPCR ligand binding; Peptideligand-binding receptors; Signal Transduction; Signaling by GPCR

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