"Dpp4" Related Products

Recombinant Mouse Dipeptidylpeptidase 4, His-tagged

Cat. No.: Dpp4-413M
Product Overview: Recombinantmouse Dpp4 protein was expressed in Murine myeloma cell line, NS0-derived, with a C-terminal9-His tag.Ser29-His760.
Description: Dpp4 is a serineexopeptidase that releases Xaa-Pro dipeptides from the N-terminus of oligo- andpolypeptides. It is a type II membrane protein consisting of a shortcytoplasmic tail, a transmembrane domain, and a long extracellular domain.
Source: Murine myeloma cellline, NS0-derived
Form: Lyophilized from a0.2 μm filtered solution in Tris and Nacl.
N-terminal Sequence: Ser29
Molecular Weight: 86 kDa
Activity: Measured by itsability to cleave the fluorogenic peptide substrate, Gly-Pro-7-amido-4-methylcoumarin(GP-AMC). The specific activity is > 2,500 pmoles/min/μg, as measuredunder the described conditions. See Activity Assay Protocol.
Endotoxin Level: <1.0 EU per 1 μgof the protein by the LAL method.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3months, -20 to -70 °C under sterile conditions after reconstitution.
Gene Name: Dpp4dipeptidylpeptidase 4 [ Mus musculus ]
Official Symbol: Dpp4
Synonyms: Dpp4; dipeptidylpeptidase4; Cd26;THAM; Dpp-4; OTTMUSP00000013700;dipeptidyl peptidase 4; DPP IV; dipeptidyl peptidase IV; thymocyte-activatingmolecule; T-cell activation antigen CD26; EC; CD26
Gene ID: 13482
mRNA Refseq: NM_010074
Protein Refseq: NP_034202
UniProt ID: P28843
Chromosome Location: 2
Pathway: Incretin Synthesis, Secretion, andInactivation; Integration of energy metabolism; Metabolism; Protein digestionand Incretin Synthesis, Secretion, and Inactivation; Integration of energymetabolism; Metabolism; Protein digestion and absorption; Regulation ofInsulin Secretion; Synthesis, Secretion, and Inactivation of Glucagon-likePeptide-1 (GLP-1)
Function: aminopeptidase activity; collagen binding;dipeptidyl-peptidase activity; hydrolase activity; peptidase activity;peptide binding; protease binding; protein homodimerization activity;receptor activity; receptor binding; serine-type endopeptidase activity;serine-type peptidase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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