Active Recombinant Mouse Dipeptidylpeptidase 4, His-tagged
Cat.No. : | Dpp4-413M |
Product Overview : | Recombinantmouse Dpp4 protein was expressed in Murine myeloma cell line, NS0-derived, with a C-terminal9-His tag.Ser29-His760. |
- Specification
- Gene Information
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Cat. No. : | Dpp4-413M |
Description : | Dpp4 is a serineexopeptidase that releases Xaa-Pro dipeptides from the N-terminus of oligo- andpolypeptides. It is a type II membrane protein consisting of a shortcytoplasmic tail, a transmembrane domain, and a long extracellular domain. |
Source : | Mammalian cells |
Form : | Lyophilized from a0.2 μm filtered solution in Tris and Nacl. |
N-terminal Sequence : | Ser29 |
Molecular Weight : | 86 kDa |
Activity : | Measured by itsability to cleave the fluorogenic peptide substrate, Gly-Pro-7-amido-4-methylcoumarin(GP-AMC). The specific activity is > 2,500 pmoles/min/μg, as measuredunder the described conditions. See Activity Assay Protocol. |
Endotoxin Level : | <1.0 EU per 1 μgof the protein by the LAL method. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3months, -20 to -70 °C under sterile conditions after reconstitution. |
Gene Name : | Dpp4dipeptidylpeptidase 4 [ Mus musculus ] |
Official Symbol : | Dpp4 |
Synonyms : | Dpp4; dipeptidylpeptidase4; Cd26;THAM; Dpp-4; OTTMUSP00000013700;dipeptidyl peptidase 4; DPP IV; dipeptidyl peptidase IV; thymocyte-activatingmolecule; T-cell activation antigen CD26; EC 3.4.14.5; CD26 |
Gene ID : | 13482 |
mRNA Refseq : | NM_010074 |
Protein Refseq : | NP_034202 |
UniProt ID : | P28843 |
Chromosome Location : | 2 |
Pathway : | Incretin Synthesis, Secretion, andInactivation; Integration of energy metabolism; Metabolism; Protein digestionand Incretin Synthesis, Secretion, and Inactivation; Integration of energymetabolism; Metabolism; Protein digestion and absorption; Regulation ofInsulin Secretion; Synthesis, Secretion, and Inactivation of Glucagon-likePeptide-1 (GLP-1) |
Function : | aminopeptidase activity; collagen binding;dipeptidyl-peptidase activity; hydrolase activity; peptidase activity;peptide binding; protease binding; protein homodimerization activity;receptor activity; receptor binding; serine-type endopeptidase activity;serine-type peptidase activity |
Products Types
◆ Recombinant Protein | ||
Dpp4-2503M | Recombinant Mouse Dpp4 Protein, His (Fc)-Avi-tagged | +Inquiry |
DPP4-10H | Active Recombinant Human DPP4 Protein (29-766aa), C-hIgG-tagged | +Inquiry |
DPP4-793H | Recombinant Human DPP4 Protein | +Inquiry |
DPP4-203H | Recombinant Human DPP4 Protein, Fc-tagged | +Inquiry |
Dpp4-2641M | Recombinant Mouse Dpp4 Protein, Myc/DDK-tagged | +Inquiry |
◆ Native Protein | ||
DPP4-197H | Native Human Dipeptidyl Peptidase IV | +Inquiry |
DPP4-31H | Active Native Human DPP4 | +Inquiry |
◆ Lysates | ||
DPP4-2979HCL | Recombinant Human DPP4 cell lysate | +Inquiry |
DPP4-733CCL | Recombinant Cynomolgus DPP4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0317 | DPPIV/CD26 Assay Kit | +Inquiry |
Kit-0315 | DPP4 Inhibitor Screening Kit | +Inquiry |
Kit-0313 | DPP IV Immunocapture Activity Assay Kit | +Inquiry |
Kit-0312 | Dipeptidyl peptidase IV Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDPP4 plays a crucial role in glucose homeostasis by cleaving incretin hormones. In diabetes, inhibiting DPP4 can enhance the action of these hormones, promoting insulin release and lowering blood sugar levels.
Common side effects of DPP4 inhibitors include respiratory and urinary tract infections, headache, and nasopharyngitis. However, they are generally well-tolerated.
Inhibitors of DPP4 are used in the treatment of type 2 diabetes to improve glycemic control. They work by prolonging the activity of incretin hormones, such as GLP-1, which stimulate insulin secretion.
DPP4 inhibitors are often used as monotherapy or in combination with other antidiabetic medications to achieve optimal glycemic control.
DPP4 inhibitors work by enhancing the effects of incretin hormones, while other diabetes medications may act on insulin sensitivity, insulin release, or glucose absorption.
Customer Reviews (3)
Write a reviewIts purity and efficacy make it an ideal choice for precise and accurate analysis, allowing me to generate reliable results.
By incorporating the DPP4 Protein into their studies, scientists can confidently conduct their research, ushering in groundbreaking discoveries and novel insights within their respective domains.
Its exceptional purity and functionality make it an ideal choice for accurate and precise analysis, ensuring reliable and reproducible results.
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