"Epor" Related Products


Recombinant Mouse Erythropoietin Receptor

Cat. No.: Epor-464M
Product Overview: Recombinant Mouse Eporprotein was expressed in Murine myeloma cell line. Ala27-Arg192.
Description: Erythropoietin (Epo)is a 34 kDa glycoprotein hormone in the type I cytokine family and is relatedto thrombopoietin. Its three N glycosylation sites, four alpha helices, and NtoCterminal disulfide bond are conserved across species. Glycosylation of Epo isrequired for biological activities in vivo. Mature mouse Epo shares 95% aminoacid sequence identity with rat Epo and 73%-82% with bovine, canine, equine, feline,human, ovine, and porcine EPO.
Source: Murine myeloma cellline, NS0-derived
Form: Lyophilized from a 0.2μm filtered solution in PBS with BSA as a carrier protein.
N-terminalSequence: Ala27
Molecular Weight: 18.6 kDa
Activity: Measuredin a cell proliferation assay using TF1 human erythroleukemic cells. Kitamura,T. et al. (1989) J. Cell Physiol. 140:323. The ED50 for this effectis typically 0.4-2 ng/mL.
Endotoxin Level: <1.0 EUper 1 μg of the protein by the LAL method.
Purity: >90%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: Reconstituteat 10 μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
Storage: Use a manualdefrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months,-20 to -70°C under sterile conditions after reconstitution.
Gene Name: Epor erythropoietinreceptor [ Mus musculus ]
Official Symbol: Epor
Synonyms: Epor; erythropoietinreceptor; EPO-R
Gene ID: 13857
mRNA Refseq: NM_010149
Protein Refseq: NP_034279
UniProt ID: P14753
Chromosome Location: 9 A3; 9 5.0 cM
Pathway: Cytokine-cytokine receptorinteraction; EPO Receptor Signaling; Hematopoietic cell lineage; Jak-STAT signalingpathway; Kit Receptor Signaling Pathway
Function: cytokine receptor activity;erythropoietin receptor activity; identical protein binding; protein binding;receptor activity; transmembrane signaling receptor activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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