Active Recombinant Mouse V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (avian), Fc-tagged
Cat.No. : | Erbb3-470M |
Product Overview : | Recombinant Mouse Erbb3protein was expressed in Murine myeloma cell line with the Fc part of mouse IgG2a.Ser20-His641. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Erbb3-470M |
Description : | Erbb3, also called HER3(human epidermal growth factor receptor 3) in humans, is a type I transmembraneglycoprotein that is a member of the ErbB family of tyrosine kinase receptorsnamed for a viral oncogene. ErbB family members serve as receptors for the EGFfamily of growth factors. Mouse Erbb3 contains a 19 amino acid (aa) signal sequence,a 622 aa extracellular domain (ECD), a 24 aa transmembrane region, and a 677 aacytoplasmic domain. |
Source : | Mammalian cells |
Form : | Lyophilized from a 0.2μm filtered solution in PBS. |
N-terminalSequence : | Ser20 |
Molecular Weight : | 95.6 kDa |
Activity : | Measuredby its ability to bind rhNRG1ß1 extracellular domain in a functional ELISA withan estimated KD < 15 nM. |
Endotoxin Level : | <1.0 EUper 1 μg of the protein by the LAL method. |
Purity : | >90%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstituteat 100 μg/mL in sterile PBS |
Storage : | Use a manualdefrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months,-20 to -70°C under sterile conditions after reconstitution. |
Gene Name : | Erbb3 v-erb-b2 erythroblastic leukemiaviral oncogene homolog 3 (avian) [ Mus musculus ] |
Official Symbol : | Erbb3 |
Synonyms : | Erbb3; v-erb-b2erythroblastic leukemia viral oncogene homolog 3 (avian); Her3; C76256; Erbb-3;Erbb3r; receptor tyrosine-protein kinase erbB-3; c-erbB-3; receptor tyrosine kinase;glial growth factor receptor; proto-oncogene-like protein c-ErbB-3; avian erythroblastosisoncogene B 3 receptor; EC 2.7.10.1 |
Gene ID : | 13867 |
mRNA Refseq : | NM_010153 |
Protein Refseq : | NP_034283 |
UniProt ID : | Q61526 |
Chromosome Location : | 10 D3; 10 70.0 cM |
Pathway : | Calcium signaling pathway;Endocytosis; ErbB signaling pathway; IL-6 signaling Pathway |
Function : | ATP binding; growth factorbinding; kinase activity; nucleotide binding; protein binding; protein heterodimerizationactivity; protein kinase activity; protein tyrosine kinase activator activity;NOT protein tyrosine kinase activity; receptor activity; receptor signaling proteintyrosine kinase activity; transferase activity; transferase activity; transmembranereceptor protein tyrosine kinase activity |
Products Types
◆ Recombinant Protein | ||
ERBB3-02HM | Recombinant Human ERBB3 Protein (E928G), His tagged | +Inquiry |
ERBB3-23H | Active Recombinant Human ERBB3 Protein | +Inquiry |
Erbb3-384M | Recombinant Mouse Erbb3 Protein, His-tagged | +Inquiry |
ERBB3-383H | Recombinant Human ERBB3 Protein, His-tagged | +Inquiry |
ERBB3-68H | Recombinant Human ERBB3 Protein (ECD), His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
ERBB3-430HCL | Recombinant Human ERBB3 cell lysate | +Inquiry |
ERBB3-1765MCL | Recombinant Mouse ERBB3 cell lysate | +Inquiry |
ERBB3-1721RCL | Recombinant Rhesus ERBB3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket