Recombinant Human CST4, His-tagged

• Cat.No.: CST4-6768H
• Product Overview: Recombinant Human CST4(27 - 146 aa) fussed with His tag at N-terminal was expressed in E. coli.

Specification

• Description: CST4 (Cystatin-S) belongs to the cystatin family. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20 mM Tris-HCl buffer, pH8.0, 10% glycerol, 1mM DTT, 50mM NaCl
• Molecular Mass: 16.8kDa (145aa), confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSSSKEE NRIIPGGIYD ADLNDEWVQR ALHFAISEYN KATEDEYYRR PLQVLRAREQ TFGGVNYFFDVEVGRTICTK SQPNLDTCAF HEQPELQKKQ LCSFEIYEVP WEDRMSLVNS RCQEA
• Purity: > 95% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CST4 cystatin S [ Homo sapiens ]
• Official Symbol: CST4
• Synonyms: cystatin-S; cystatin 4; cystatin-4; cystatin-SA-III; salivary acidic protein 1
• Gene ID: 1472
• mRNA Refseq: NM_001899
• Protein Refseq: NP_001890
• MIM: 123857
• UniProt ID: P01036
• Chromosome Location: 20p11.21
• Pathway: Salivary secretion, organism-specific biosystem; Salivary secretion, conserved biosystem
• Function: cysteine-type endopeptidase inhibitor activity