Recombinant Human Homer Homolog 3 (Drosophila), His-tagged HOMER3-67H

Recombinant Human Homer Homolog 3 (Drosophila), His-tagged

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Recombinant Human Homer Homolog 3 (Drosophila), His-tagged

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Cat. No. : HOMER3-67H
Product Overview : Recombinant humanHOMER3 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography.
Description : HOMER3, also knownas homer protein homolog 3, is a member of the HOMER family of postsynapticdensity scaffolding proteins that share a similar domain structure consistingof an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1domain which mediates protein-protein interactions, and a carboxy-terminalcoiled-coil domain and two leucine zipper motifs that are involved inself-oligomerization
Form : Liquid. 20mMTris-HCl buffer (pH8.0) containing 30% glycerol, 0.15M NaCl, 1mM DTT
Molecular Weight : 42.5 kDa (386aa),confirmed by MALDI-TOF
Purity : > 90% by SDS -PAGE
Concentration : 1 mg/ml (determinedby Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGSHMMSTAR EQPIFSTRAH VFQIDPATKR NWIPAGKHAL TVSYFYDATR NVYRIISIGGAKAIINSTVT PNMTFTKTSQ KFGQWADSRA NTVYGLGFAS EQHLTQFAEK FQEVKEAARL AREKSQDGGELTSPALGLAS HQVPPSPLVS ANGPGEEKLF RSQSADAPGP TERERLKKML SEGSVGEVQW EAEFFALQDSNNKLAGALRE ANAAAAQWRQ QLEAQRAEAE RLRQRVAELE AQAASEVTPT GEKEGLGQGQ SLEQLEALVQTKDQEIQTLK SQTGGPREAL EAAEREETQQ KVQDLETRNA ELEHQLRAME RSLEEARAER ERARAEVGRAAQLLDVSLFE LSELREGLAR LAEAAP
Storage : Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles
Rendering based on PDB 2P8V. :

Gene Name : HOMER3homer homolog 3 (Drosophila) [ Homo sapiens ]
Official Symbol : HOMER3
Synonyms : HOMER3; homer homolog 3 (Drosophila);homer protein homolog 3; HOMER 3; HOME3_HUMAN; HOMER 3; Homer 3D protein;Homer homolog 3 (Drosophila); Homer neuronal immediate early gene 3; Homerprotein homolog 3; Homer-3; Homer3; VESL3; Homer, neuronal immediate earlygene, 3; VESL3; HOMER-3
Gene ID : 9454
mRNA Refseq : NM_001145724
Protein Refseq : NP_001139196
MIM : 604800
Uniprot ID : Q9NSC5
Chromosome Location : 19p13.1
Pathway : Glutamatergic synapse,organism-specific biosystem; Glutamatergic synapse, conserved biosystem; TCell Receptor Signaling Pathway, organism-specific biosystem
Function : protein C-terminus binding; proteinbinding; protein domain specific binding

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