"THAP1" Related Products

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Recombinant Human THAP Domain Containing, Apoptosis Associated Protein 1, His-tagged

Cat. No.: THAP1-5594H
Product Overview: Recombinant humanTHAP1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Description: THAPdomain-containing protein 1, also known as THAP1, is a 213 amino acid proteinthat localizes to the nucleoplasm and contains one THAPtype zinc finger, aconserved DNA-binding domain. It is a DNA-binding transcription regulatorthat regulates endothelial cell proliferation and G1/S cell-cycleprogression. THAP1 may also have pro-apoptopic activity by potentiating bothserum-withdrawal and TNF-induced apoptosis.
Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 2M Urea, 10% glycerol, 1mM DTT, 0.2M NaCl.
Molecular Weight: 27.5 kDa(237aa)
Purity: > 85%by SDS-PAGE
Concentration: 1 mg/ml(determined by Bradford assay)
Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMVQSCS AYGCKNRYDK DKPVSFHKFP LTRPSLCKEW EAAVRRKNFKPTKYSSICSE HFTPDCFKRE CNNKLLKENA VPTIFLCTEP HDKKEDLLEP QEQLPPPPLP PPVSQVDAAIGLLMPPLQTP VNLSVFCDHN YTVEDTMHQR KRIHQLEQQV EKLRKKLKTA QQRCRRQERQ LEKLKEVVHFQKEKDDVSER GYVILPNDYF EIVEVPA
Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: THAP1 THAP domain containing,apoptosis associated protein 1 [ Homo sapiens ]
Official Symbol: THAP1
Synonyms: THAP1; THAP domain containing, apoptosisassociated protein 1; DYT6; FLJ10477; MGC33014; THAP domain-containingprotein 1; 4833431A01Rik; THAP domain protein 1; nuclear proapoptotic factor;dystonia 6, torsion (autosomal dominant); OTTHUMP00000229191;OTTHUMP00000229192; OTTHUMP00000229193
Gene ID: 55145
mRNA Refseq: NM_018105
Protein Refseq: NP_060575
MIM: 609520
UniProt ID: Q9NVV9
Chromosome Location: 8p11.21
Function: metal ion binding; sequence-specific DNAbinding; zinc ion binding

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