"RIPK3" Related Products

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Recombinant Human RIPK3, GST-tagged

Cat. No.: RIPK3-2899H
Product Overview: RecombinantHuman RIPK3 produced by wheat germ expression system in vitro contains GSTtag at N-terminus and is purified by glutathione sepharose 4 fast flow.
Description: The productof this gene is a member of the receptor-interacting protein (RIP) family ofserine/threonine protein kinases, and contains a C-terminal domain uniquefrom other RIP family members. The encoded protein is predominantly localizedto the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent onnovel nuclear localization and export signals. It is a component of the tumornecrosis factor (TNF) receptor-I signaling complex, and can induce apoptosisand weakly activate the NF-kappaB transcription factor.
Source: wheat germ
Applications: Kinase Assay; ELISA ; Antibody Production; WesternBlot; Protein Array
StorageBuffer: 50mM Tris-HCl, 10 mM reduced Glutathione, pH8.0 in the elution buffer.
Storage: Store at -80℃. Aliquot toavoid repeated freezing and thawing.
OfficialSymbol: RIPK3
Gene Name: RIPK3 receptor-interactingserine-threonine kinase 3 [ Homo sapiens ]
Synonyms: receptor-interactingserine-threonine kinase 3; RIP3; Receptor-interacting protein 3; RIP-3; RIP-likeprotein kinase 3; OTTHUMP00000164791; receptor interacting protein3; receptor-interactingserine/threonine-protein kinase 3; EC 2.7.11.1; receptor-interactingserine/threonine-protein kinase 3
Gene ID: 11035
mRNA Refseq: NM_006871
Protein Refseq: NP_006862
MIM: 605817
UniProt ID: Q9Y572
Chromosome Location: 14q12
Pathway: CytosolicDNA-sensing pathway; Immune System; Innate Immune System
Function: ATPbinding; nucleotide binding; nucleotide binding

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