||RecombinantHuman RIPK3 produced by wheat germ expression system in vitro contains GSTtag at N-terminus and is purified by glutathione sepharose 4 fast flow.
||The productof this gene is a member of the receptor-interacting protein (RIP) family ofserine/threonine protein kinases, and contains a C-terminal domain uniquefrom other RIP family members. The encoded protein is predominantly localizedto the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent onnovel nuclear localization and export signals. It is a component of the tumornecrosis factor (TNF) receptor-I signaling complex, and can induce apoptosisand weakly activate the NF-kappaB transcription factor.
||Kinase Assay; ELISA ; Antibody Production; WesternBlot; Protein Array
||50mM Tris-HCl, 10 mM reduced Glutathione, pH8.0 in the elution buffer.
||Store at -80℃. Aliquot toavoid repeated freezing and thawing.