"HTR2A" Related Products


Recombinant Human HTR2A, His-tagged

Cat. No.: HTR2A-1561H
Product Overview: Recombinant Human HTR2A encoding human5-hydroxytryptamine receptor 2A (a.a.1–471) was fused a His-tag.
Description: This gene encodes one of the receptors for serotonin, aneurotransmitter with many roles. Mutations in this gene are associated withsusceptibility to schizophrenia and obsessive-compulsive disorder, and arealso associated with response to the antidepressant citalopram in patientswith major depressive disorder (MDD). MDD patients who also have a mutationin intron 2 of this gene show a significantly reduced response to citalopramas this antidepressant downregulates expression of this gene. Multipletranscript variants encoding different isoforms have been found for thisgene.
Applications: Western Blot; ELISA
Purity: >90%, as determined by SDS-PAGE under reducingconditions
Formulation: Liquid
Storage: Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoidrepeated freeze-thaw
Gene Name: HTR2A 5-hydroxytryptamine(serotonin) receptor 2A, G protein-coupled [ Homo sapiens ]
Official Symbol: HTR2A
Synonyms: HTR2; 5-HT2A; 5-hydroxytryptaminereceptor 2A; 5-HT-2A; 5-HT2 receptor; serotonin 5-HT-2A receptor
Gene ID: 3356
mRNA Refseq: NM_000621
Protein Refseq: NP_000612
MIM: 182135
UniProt ID: P78352
Chromosome Location: 13q14-q21
Pathway: Amine ligand-binding receptors; Calciumsignaling pathway; GPCR downstream signaling
Function: drug binding; receptoractivity

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