Recombinant Murine BMP4
| Cat.No. : | Bmp4-578TM |
| Product Overview : | Recombinant Murine BMP4 encoding murine BMP4 was expressedin E.coli. |
- Specification
- Gene Information
- Related Products
| Cat. No. : | Bmp4-578TM |
| Description : | Bone morphogenetic proteins (BMPs) constitute a subfamilywithin the TGF-β superfamily of structurally related signaling proteins.Members of this superfamily are widely distributed throughout the body andare involved in diverse physiological processes during both pre- andpostnatal life. Like BMP-7, BMP-4 is involved in the development and maintenanceof bone and cartilage. Reduced expression of BMP-4 is associated with anumber of bone diseases, including the heritable disorder FibrodysplasiaOssificans Progressiva. PeproTech's E.coli derived murine BMP-4 is a fullyactive homodimeric protein consisting of two 106 amino acid subunits whichcorrespond to amino acids 303-408 of the full length BMP-4 precursor. |
| Source : | E.coli |
| Biological Activity : | Determined by its ability to induce alkaline phosphataseproduction by ATDC-5 cells. The expected ED50 for this effect is 5-15 ng/ml. |
| AA Sequence : | KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNSTNHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCRKKNK NCRRHSLYVDFSDVGWNDWI VAPPGYQAFY CHGDCPFPLA DHLNSTNHAI VQTLVNSVNS SIPKACCVPT ELSAISMLYLDEYDKVVLKN YQEMVVEGCG CR |
| Purity : | Greater than 98% by SDS-PAGE gel and HPLC analyses. |
| Gene Name : | Bmp4 bonemorphogenetic protein4 [ Mus musculus ] |
| Official Symbol : | Bmp4 |
| Synonyms : | Bmp4; bonemorphogenetic protein 4; Bmp-4; Bmp2b; Bmp2b1;Bmp2b-1; BMP-2B; bonemorphogenetic protein 2B |
| Gene ID : | 12159 |
| mRNA Refseq : | NM_007554 |
| Protein Refseq : | NP_031580 |
| UniProt ID : | Q3ULR1 |
| Chromosome Location : | 14 C1 |
| Pathway : | Adipogenesis; Basalcell carcinoma; ESCPluripotency Pathways; Hedgehog signaling pathway;Pathways in cancer; PluriNetWork;TGF Beta Signaling Pathway; TGF-betasignaling pathway |
| Function : | BMP receptor binding; chemoattractant activity;cytokine activity; growth factor activity; heparinbinding; protein binding;protein homodimerization activity |
Products Types
| ◆ Lysates | ||
| BMP4-8431HCL | Recombinant Human BMP4 293 Cell Lysate | +Inquiry |
| BMP4-8432HCL | Recombinant Human BMP4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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