"ARPC5" Related Products

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Recombinant Human ARPC5, His-tagged

Cat. No.: ARPC5-3539H
Product Overview: Recombinant humanARPC5 protein, fused to His-tag at N-terminus, was expressed in E. coliand purified by using conventional chromatography techniques.
Description: ARPC5 is a 151 aminoacid subunit of the Arp2/3 complex. Thought to play a role in maintaining theintegrity of Arp2/3, ARPC5 is a substrate for MAPKAPK-2 which, throughphosphorylation of ARPC5, may participate in Arp2/3 regulatory functions andremodeling of the Actin cytoskeleton. Two isoforms of ARPC5 exist due toalternative splicing events.
Application: SDS-PAGE
Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 1mM DTT, 50% glycerol, 0.1M NaCl.
Molecular Weight: 18.4 kDa (171aa),confirmed by MALDI-TOF
Purity: > 90% by SDS-PAGE
Concentration: 0.5 mg/ml(determined by Bradford assay)
Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSHMSKNTVSSAR FRKVDVDEYD ENKFVDEEDG GDGQAGPDEG EVDSCLRQGNMTAALQAALK NPPINTKSQA VKDRAGSIVL KVLISFKAND IEKAVQSLDK NGVDLLMKYI YKGFESPSDNSSAMLLQWHE KALAAGGVGS IVRVLTARKT V
Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
OfficialSymbol: ARPC5
Gene Name: ARPC5 actin related protein 2/3complex, subunit 5, 16kDa [ Homo sapiens ]
Synonyms: ARPC5; actinrelated protein 2/3 complex, subunit 5, 16kDa; ARC16;p16-Arc; MGC88523; dJ127C7.3; actin-related protein 2/3 complex subunit 5;OTTHUMP00000033266; OTTHUMP00000033267; OTTHUMP00000038626; arp2/3 complex 16kDa subunit; Arp2/3 protein complex subunit p16; p16-ARC
Gene ID: 10092
mRNA Refseq: NM_005717
Protein Refseq: NP_005708
MIM: 604227
UniProt ID: O15511
Chromosome Location: 1p25.3
Pathway: B Cell ReceptorSignaling Pathway; CDC42 signaling events; ErbB1 downstream signaling; Fcgamma R-mediated phagocytosis; Pathogenic Escherichia coli infection; RAC1signaling pathway; Regulation of Actin Cytoskeleton; Salmonella infection;Shigellosis; Bacterial invasion of epithelial cells
Function: actin binding; protein binding;structural constituent of cytoskeleton

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