Recombinant Human CLPP, His-tagged
Cat.No. : | CLPP-3538H |
Product Overview : | Recombinant humanCLPP protein was expressed in E. coli and purified by using conventionalchromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CLPP-3538H |
Description : | CLPP belongs to thepeptidase family S14. CLPP cleaves peptides in various proteins in a processthat requires ATP hydrolysis. CLPP, the catalytic core of the Clp proteolyticcomplex, is widely involved in many cellular processes via the regulation ofintracellular protein quality. CLPP may be responsible for a fairly generaland central housekeeping function rather than for the degradation of specificsubstrates. |
Application : | SDS-PAGE |
Form : | Liquid. In 20mM Tris-HClbuffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200mM NaCl. |
Molecular Weight : | 24.2 kDa (222aa),confirmed by MALDI-TOF |
Purity : | > 90% by SDS-PAGE |
Concentration : | 0.5 mg/ml(determined by Bradford assay) |
Sequences of aminoacids : | MPLIPIVVEQTGRGERAYDI YSRLLRERIV CVMGPIDDSV ASLVIAQLLF LQSESNKKPI HMYINSPGGV VTAGLAIYDTMQYILNPICT WCVGQAASMG SLLLAAGTPG MRHSLPNSRI MIHQPSGGAR GQATDIAIQA EEIMKLKKQLYNIYAKHTKQ SLQVIESAME RDRYMSPMEA QEFGILDKVL VHPPQDGEDE PTLVQKEPVE AAPAAEPVPAST |
Storage : | Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
OfficialSymbol : | CLPP |
Gene Name : | CLPP ClpP caseinolyticpeptidase, ATP-dependent, proteolytic subunit homolog (E. coli) [ Homosapiens ] |
Synonyms : | CLPP; ClpPcaseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli);putative ATP-dependent Clp protease proteolytic;subunit, mitochondrial; endopeptidase Clp; ATP-dependent protease ClpAP,proteolytic subunit, human; ClpP caseinolytic peptidase ATP-dependent,proteolytic subunit; ClpP caseinolytic protease, ATP-dependent, proteolyticsubunit homolog; EC 3.4.21.92; putative ATP-dependent Clp proteaseproteolytic subunit, mitochondrial |
Gene ID : | 8192 |
mRNA Refseq : | NM_006012 |
Protein Refseq : | NP_006003 |
MIM : | 601119 |
UniProt ID : | Q16740 |
Chromosome Location : | 19p13.3 |
Function : | ATP binding; nucleotidebinding; peptidase activity; protein binding; serine-type endopeptidaseactivity |
Products Types
◆ Recombinant Protein | ||
CLPP-1766M | Recombinant Mouse CLPP Protein, His (Fc)-Avi-tagged | +Inquiry |
Clpp-2197M | Recombinant Mouse Clpp Protein, Myc/DDK-tagged | +Inquiry |
CLPP-1512H | Recombinant Human CLPP Protein, GST-tagged | +Inquiry |
CLPP-1971C | Recombinant Clostridium Botulinum CLPP Protein (1-194 aa), His-SUMO-tagged | +Inquiry |
CLPP-2847Z | Recombinant Zebrafish CLPP | +Inquiry |
◆ Lysates | ||
CLPP-7434HCL | Recombinant Human CLPP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionTargeting CLPP therapeutically could offer potential in diseases related to mitochondrial dysfunction and aging.
CLPP activity is tightly regulated to ensure balanced protein turnover in mitochondria.
Dysregulation of CLPP is linked to various diseases, including mitochondrial disorders.
It helps in degrading misfolded or damaged proteins, maintaining mitochondrial function.
Proper functioning of CLPP is vital for mitochondrial health and energy production.
CLPP levels and activity are associated with aging, influencing cellular senescence and longevity.
CLPP plays a crucial role in mitochondrial protein degradation and quality control.
Customer Reviews (3)
Write a reviewVery high purity level.
Worked excellently in experiments.
Product was well packaged.
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