Recombinant Human Suppressor Of Cytokine Signaling 3, GST-tagged
Cat.No. : | SOCS3-6938H |
Product Overview : | RecombinantHuman SOCS3 protein was expressed as GST-tagged fusion protein by E. coli andpurified by GSH-sepharose. |
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Cat. No. : | SOCS3-6938H |
Description : | Thisgene encodes a member of the suppressor of cytokine signaling, family. SSIfamily members are cytokine-inducible negative regulators of cytokinesignaling. The expression of this gene is induced by various cytokines,including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by thisgene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. |
Source : | E. coli |
Species : | Human |
Antigen peptide : | 1-225aa |
Expression Vector : | PGEX-4T |
Full length : | True |
Reconstitution : | 1M PBS (58mMNa2HPO4,17mM NaH2PO4, 68mM NaCl, pH 8.0) added with 100mM GSH and 1% TritonX-100,15%glycerol. |
Storage : | The protein is stored in PBS buffer at -20°C. Repeated freeze-thaw cycles should be avoided. |
Gene Name : | SOCS3 suppressor ofcytokine signaling 3 [ Homo sapiens ] |
Official Symbol : | SOCS3 |
Synonyms : | SOCS3;suppressor of cytokine signaling 3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3;CIS-3; STAT-induced STAT inhibitor 3; cytokine-induced SH2 protein 3;cytokine-inducible SH2 protein 3; MGC71791 |
Gene ID : | 9021 |
mRNA Refseq : | NM_003955 |
Protein Refseq : | NP_003946 |
MIM : | 604176 |
UniProt ID : | P35270 |
Chromosome Location : | 2p14-p12 |
Pathway : | ATF-2 transcription factor network;Adaptive Immune System; Adipocytokine signaling pathway; Adipogenesis; ClassI MHC mediated antigen processing & presentation; Cytokine Signaling inImmune system; ECS complex; EGFR1 Signaling Pathway; EPO signaling pathway;Growth hormone receptor signaling; Hepatitis C; Herpes simplex infection;IL-2 Signaling Pathway; IL-3 Signaling Pathway; IL-4 signaling Pathway; IL-6Signaling Pathway |
Function : | protein kinase inhibitor activity |
Products Types
◆ Recombinant Protein | ||
SOCS3-4218R | Recombinant Rhesus Macaque SOCS3 Protein, His (Fc)-Avi-tagged | +Inquiry |
SOCS3-1526R | Recombinant Rat SOCS3 Protein (1-225 aa), His-tagged | +Inquiry |
SOCS3-5324R | Recombinant Rat SOCS3 Protein, His (Fc)-Avi-tagged | +Inquiry |
SOCS3-2068H | Recombinant Human SOCS3 Protein, His (Fc)-Avi-tagged | +Inquiry |
SOCS3-3895H | Recombinant Human SOCS3 protein(Met1-Leu225), His&Trx-tagged | +Inquiry |
◆ Lysates | ||
SOCS3-1580HCL | Recombinant Human SOCS3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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