Native Human Haptoglobin
Cat.No. : | HP-4387H |
Product Overview : | Human HP produced from pooled human plasma corresponding to the Mw of isotypes of HP at 86kD and 200kD. |
- Specification
- Gene Information
- Related Products
Description : | HP is a glycoprotein which is synthesized in the liver and circulates in the blood. HP is produced typically by hepatocytes but also by other tissues: e.g. skin, lung, and kidney. It is a positive acute phase protein that binds free hemoglobin and removes it from the circulation to prevent kidney injury, and iron loss following hemolysis. The HP-hemoglobin complex is subsequently removed by the reticuloendothelial system (generally the spleen). As the reticuloendothelial system removes the HP-hemoglobin complex from the body, HP levels are reduced in hemolytic anaemias. In the course of binding hemoglobin, HP sequesters the iron inside hemoglobin, preventing iron-utilizing bacteria from benefitting from hemolysis. |
Source : | Pooled human plasma |
Species : | Human |
Form : | Lyophilized from 0.02M NH4HCO3. May contain traces of buffer salts. |
Purity : | Greater than 96.0%. |
Storage : | Human HP although stable at room temperature for 3 weeks, should be stored between 2-8°C. |
Gene Name : | HP haptoglobin [ Homo sapiens ] |
Official Symbol : | HP |
Synonyms : | HP; haptoglobin; zonulin; binding peptide; haptoglobin alpha(1S)-beta; haptoglobin alpha(2FS)-beta; haptoglobin, beta polypeptide; haptoglobin, alpha polypeptide; BP; HPA1S; HP2ALPHA2; MGC111141; |
Gene ID : | 3240 |
mRNA Refseq : | NM_001126102 |
Protein Refseq : | NP_001119574 |
MIM : | 140100 |
UniProt ID : | P00738 |
Chromosome Location : | 16q22.2 |
Pathway : | amb2 Integrin signaling, organism-specific biosystem; |
Function : | catalytic activity; hemoglobin binding; serine-type endopeptidase activity; |
Products Types
◆ Recombinant Protein | ||
HP-079H | Recombinant Human HP Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
HP-1891H | Recombinant Human HP Protein, MYC/DDK-tagged | +Inquiry |
HP-2770G | Recombinant Goat HP Protein, His&SUMO-tagged | +Inquiry |
HP-5001H | Recombinant Human HP Protein, GST-tagged | +Inquiry |
Hp-1162M | Recombinant Mouse Hp Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
HP-133B | Native Bovine Haptoglobin | +Inquiry |
Hp-134M | Native Mouse Haptoglobin | +Inquiry |
HP-75C | Native Canine Haptoglobin | +Inquiry |
◆ Lysates | ||
HP-5408HCL | Recombinant Human HP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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