"ASGR1" Related Products


Recombinant Human ASGR1, His-tagged

Cat. No.: ASGR1-589H
Product Overview: Recombinant human ASGR1 with apolyhistidine tag at the N-terminus was expressed in Human Cells, 28.8 kDa (246aa).
Description: This geneencodes a subunit of the asialoglycoprotein receptor. This receptor is atransmembrane protein that plays a critical role in serum glycoproteinhomeostasis by mediating the endocytosis and lysosomal degradation ofglycoproteins with exposed terminal galactose or N-acetylgalactosamineresidues. The asialoglycoprotein receptor may facilitate hepatic infection bymultiple viruses including hepatitis B, and is also a target forliver-specific drug delivery. The asialoglycoprotein receptor is ahetero-oligomeric protein composed of major and minor subunits, which areencoded by different genes. The protein encoded by this gene is the moreabundant major subunit. Alternatively spliced transcript variants encodingmultiple isoforms have been observed for this gene.
Source: HumanCells
Species: Human
Purity: >90 % as determined by SDS-PAGE.
Endotoxin: <1.0 EU per μg of the protein as determined by the LAL method.
Stability: Samplesare stable for up to twelve months from date of receipt at -70 °C.
Predicted N terminal: His
Formulation: Lyophilizedfrom 0.2 μm filtered solution of. Normally 5 % - 8 % trehalose and mannitolare added as protectants before lyophilization.
Storage: Storeit under sterile conditions at -70 °C.It is recommended that the protein be aliquoted for optimal storage. Avoidrepeated freeze-thaw cycles.
OfficialSymbol: ASGR1
Gene Name: ASGR1 asialoglycoprotein receptor1 [ Homo sapiens ]
Synonyms: ASGR1;asialoglycoprotein receptor 1; HL-1; ASGPR; ASGPR1; CLEC4H1; hepatic lectinH1; C-type lectin domain family 4 member H1; OTTHUMP00000128354; ASGP-R 1
Gene ID: 432
mRNA Refseq: NM_001197216
Protein Refseq: NP_001184145
MIM: 108360
UniProt ID: P07306
Chromosome Location: 17p13.2
Function: asialoglycoproteinreceptor activity; metal ion binding; protein binding

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