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Recombinant Human WNT3, GST-tagged

Cat.No. : WNT3-5161H
Product Overview : Recombinant Human WNT3 encoding human full-length ORF(1 a.a. - 385 a.a.), fused a GST-tag at N-treminal was expressed in Wheat germ.
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  • Gene Information
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Cat. No. : WNT3-5161H
Description : WNT3 belongs to the Wnt family of signaling proteins that play a key role in maintaining the integrity of embryonic and adult tissues. Expression of WNT3 occurs primarily along the dorsal midline across overlapping regions of the Central Nervous System (CNS). WNT3 signaling is essential for various morphogenetic events including embryonic patterning, cell determination, cell proliferation, CNS development, and cytoskeletal formation.
Source : Wheat germ
Species : Human
Purification : Glutathione Sepharose 4 Fast Flow
Formulation : Liquid. 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Sequence : MEPHLLGLLLGLLLGGTRVLAGYPI WWSLALGQQYTSLGSQPLLCGSIPG LVPKQLRFCRNYIEIMPSVAEGVKL GIQECQHQFRGRRWNCTTIDDSLAI FGPVLDKATRESAFVHAIASAGVAF AVTRSCAEGTSTICGCDSHHKGPP GEGWKWGGCSEDADFGVLVSREFAD ARENRPDARSAMNKHNNEAGRTTIL DHMHLKCKCHGLSGSCEVKT CWWAQPDFRAIGDFLKDKYDSASEM VVEKHRESRGWVETLRAKYSLFKPP TERDLVYYENSPNFCEPNPETG SFGTRDRTCNVTSHGIDGCDLLCCG RGHNTRTEKRKEKCHCIFHWCCYVS CQECIRIYDVHTCK
Storage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.
OfficialSymbol : WNT3
Gene Name : WNT3 wingless-type MMTV integration site family, member 3 [ Homo sapiens ]
Synonyms : wingless-type MMTV integration site family, member 3; INT4; Proto-oncogene Int-4 homolog; MGC131950; MGC138321; MGC138323; Proto oncogene Int 4 homolog; Proto oncogene Wnt 3; Wnt 3 proto oncogene protein; WNT 3 proto oncogene protein precursor
Gene ID : 7473
mRNA Refseq : NM_030753.3
Protein Refseq : NP_110380.1
MIM : 165330
UniProt ID : P56703
Chromosome Location : 17q21
Pathway : Basal cell carcinoma; Class B/2 (Secretin family receptors); DNA damage response (only ATM dependent); GPCR ligand binding; HTLV-I infection; Hedgehog signaling pathway; Melanogenesis; Pathways in cancer; Signaling by GPCR; Wnt Signaling Pathway; Wnt Signaling Pathway Net-Path; Wnt Signaling Pathway and Pluripotency; Wnt signaling network
Function : Frizzled binding; Frizzled-2 binding; Protein domain specific binding; receptor agonist activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How can WNT3 be targeted for therapeutic purposes? 11/21/2019

Researchers are exploring various approaches, including small molecules and biologics, to modulate WNT3 signaling for therapeutic benefits.

How is WNT3 involved in tissue regeneration? 09/10/2019

WNT3 can promote tissue regeneration by activating stem cells and facilitating tissue repair processes.

Can WNT3 be used in tissue engineering? 11/17/2018

WNT3 can be explored in tissue engineering to enhance the development and integration of engineered tissues and organs.

Can WNT3 be used in regenerative medicine? 12/13/2017

WNT3 holds promise in regenerative medicine for its potential to enhance tissue regeneration, but more research is needed for practical applications.

Are there clinical trials related to WNT3 protein? 09/05/2016

Clinical trials may be investigating the role of WNT3 and related pathways in various diseases, but you would need to check the latest clinical trial databases for specific studies.

Customer Reviews (3)

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Reviews
10/14/2022

    I am extremely satisfied with the high performance and the exceptional support associated with this protein, as it has greatly contributed to the success of my scientific endeavors.

    07/16/2018

      Their expertise and prompt assistance have been instrumental in overcoming challenges and optimizing the use of the WNT3 protein in my studies.

      01/24/2018

        the manufacturer's commitment to delivering excellent technical support has proven to be invaluable in troubleshooting any issues that arose during my experiments.

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