Mouse Anti-Human ADAM Metallopeptidase Domain 12 Monoclonal Antibody

• Cat.No.: CABT-676MH
• Product Overview: Mouse Anti-Human ADAM metallopeptidase domain 12 Monoclonal Antibody.

Specification

• Cat. No.: CABT-676MH
• Antigen Dscription: This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.
• Host Animal: Mouse
• Species Reactivity: Human
• Immunogen: A recombinant polypeptide corresponding to amino acids 208-305 of human ADAM12, expressed as a GST fusion protein.
• Clone: 2H4
• Isotype: IgG3
• Format: Purified
• Presentation: Liquid; In PBS, pH 7.2, containing no preservative.
• Applications: ELISA (this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 μg/well, 100 μl total volume. Variables associated with assay conditions will dictate the proper working dilution); Immunoblotting (1-5 μg/ml).
• Storage: Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.
• Officialsymbol: ADAM12

Gene Information

• Gene Name: ADAM12 ADAM metallopeptidase domain 12 [ Homo sapiens ]
• Synonyms: ADAM12; ADAM metallopeptidase domain 12; MCMP; MCMPMltna; MLTN; MLTNA; A Disintegrin and Metalloprotease Domain 12 S isoform; ADAM12 precursor (EC 3.4.24); Meltrin alpha; ADAM12 ADAM metallopeptidase domain 12; OTTHUMP00000020727; OTTHUMP00000046766; a disintegrin and metalloproteinase domain 12 (meltrin alpha); EC 3.4.24.; A disintegrin and metalloproteinase domain 12
• Gene ID: 8038
• mRNA Refseq: NM_003474
• Protein Refseq: NP_003465
• MIM: 602714
• UniProt ID: O43184
• Chromosome Location: 10q26.3
• Pathway: Signaling by EGFR
• Function: SH3 domain binding; metal ion binding ; metalloendopeptidase activity; peptidase activity; protein binding; zinc ion binding