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Recombinant Human NTF2-Like Export Factor 1, His-tagged

Cat.No. : NXT1-3523H
Product Overview : Recombinant human NXT1 protein, fused to His-tag at N-terminus, was expressed in E.coliand purified by using conventional chromatography (1-140aa).
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  • Gene Information
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Cat. No. : NXT1-3523H
Description : NXT1 functions as a nuclear export factor in both RAN (Ras-related nuclear protein) and CRM1 (required for chromosome region maintenance) dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. This protienheterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl
Molecular Weight : 18.0 kDa (160aa) confirmed by MALDI-TOF
Purity : >85% by SDS - PAGE
Concentration : 0.25 mg/ml (determined by BCAassay)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MASVDFKTYV DQACRAAEEF VNVYYTTMDK RRRLLSRLYM GTATLVWNGN AVSGQESLSE FFEMLPSSEF QISVVDCQPV HDEATPSQTT VLVVICGSVK FEGNKQRDFN QNFILTAQAS PSNTVWKIAS DCFRFQDWAS
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Gene Name : NXT1 NTF2-like export factor 1 [ Homo sapiens ]
Synonyms : NXT1; NTF2-like export factor 1; P15; MTR2; protein p15; NTX2-like export factor1; NUTF-like export factor 1; NTF2-related export protein 1
Gene ID : 29107
mRNA Refseq : NM_013248
Protein Refseq : NP_037380
MIM : 605811
UniProt ID : Q9UKK6
Chromosome Location : 20p12-p11.2
Function : Ran GTPase binding; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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