Expand| Cat. No. : | RHOB-3529H |
| Product Overview : | Recombinant human RhoB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (1-193aa). |
| Description : | Rho-related GTP-binding protein RhoB, also known asRhoB,is a member of the Rho GTP-binding protein family. RhoB mediates apoptosis in neoplastically transformed cells after DNA damage. It plays a negative role in tumorigenesis as deletion causes tumor formation. |
| Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT,20% glycerol, 0.2mM NaCl |
| Molecular Weight : | 23.9kDa (213aa), confirmed by MALDI-TOF(Molecular weight on SDS-PAGE will appear higher) |
| Purity : | > 90% by SDS - PAGE |
| Concentration : | 0.25mg/ml (determined by Bradford assay) |
| Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MAAIRKKLVV VGDGACGKTC LLIVFSKDEF PEVYVPTVFE NYVADIEVDG KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSVDSPD SLENIPEKWV PEVKHFCPNV PIILVANKKD LRSDEHVRTE LARMKQEPVR TDDGRAMAVR IQAYDYLECS AKTKEGVREV FETATRAALQ KRYGSQNGCI NCC |
| Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| Gene Name : | RHOB ras homolog gene family, member B [ Homo sapiens ] |
| Synonyms : | RHOB; ARH6; ARHB; RHOH6; MST081; MSTP081; rho-related GTP-binding protein RhoB; h6; oncogene RHO H6; rho cDNA clone 6; Aplysia RAS-related homolog 6 |
| Gene ID : | 388 |
| mRNA Refseq : | NM_004040 |
| Protein Refseq : | NP_004031 |
| MIM : | 165370 |
| UniProt ID : | P62745 |
| Chromosome Location : | 2p24 |
| Function : | GDP binding; GTP binding; GTPase activity; nucleotide binding; protein binding |
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