Mouse Anti-Human Intercellular adhesion molecule 2 Monoclonal Antibody


Home / Products / Antibody / Mouse Anti-Human Intercellular adhesion molecule 2 Monoclonal Antibody

Mouse Anti-Human Intercellular adhesion molecule 2 Monoclonal Antibody

ICAM2 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : CAB11557MH
Product Overview : Mouse Monoclonal Antibody to Human Intercellular adhesion molecule 2
Antigen Description : Intercellular adhesion molecule 2 (ICAM2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type Itransmembrane glycoprotein with two Ig-like C2-type domains, and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). ICAM2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocyte with other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. This protein can be encoded by several transcript variants.
Specificity : Human ICAM-2 / CD102. No cross-reactivity with human cell lysate ( 293 cell line ) in WB and ELISA.
Immunogen : Recombinant Human ICAM-2 / CD102 Protein
Host : Mouse
Isotype : Mouse IgG1
Species : Human
Cross Reactivity : 1A5C1
Clone : 2B6D2
Applications : WB; ELISA
Dilution : Western blot: This antibody can be used at 0.1-0.2μg/mL with the appropriate secondary reagents to detect ICAM2-His in WB. Using a DAB detection system, the detection limit for ICAM2-His is approximately 8 ng/lane under non-reducing conditions and 2 ng/lane under reducing conditions.Direct ELISA: This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect ICAM2-His. The detection limit for ICAM2-His is approximately 0.00975 ng/well.
Preparation : This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, human cell-derived, recombinant Human ICAM-2 / CD102 (rh ICAM-2 / CD102; NP_777596.2; Met 1 - Gln 223). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Format : 0.2 μm filtered solution in PBS with 5% trehalose
Storage : This antibody can be stored at 2-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 to -70 °C. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Gene Name : ICAM2 intercellular adhesion molecule 2 [ Homo sapiens ]
Official Symbol : ICAM2
Synonyms : ICAM2; intercellular adhesion molecule 2; CD102; ICAM-2;
Gene ID : 3384
mRNA Refseq : NM_000873
Protein Refseq : NP_000864
MIM : 146630
UniProt ID : P13598
Chromosome Location : 17q23-q25
Pathway : Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem; Natural killer cell mediated cytotoxicity, organism-specific biosystem;
Function : integrin binding;

Online Inquiry

  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information
  • Note: There will be extra charge for optional service!

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved.