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Recombinant Mouse Chi3l1 protein, His-tagged

Cat.No. : Chi3l1-6906M
Product Overview : Recombinant Mouse Chi3l1 protein(Q61362-2)(Met1-Ala381), fused with His tag, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Mouse
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Molecular Mass : The secreted recombinant mouse CHI3L1 comprises 371 amino acids and has a calculated molecular mass of 42.3 kDa. As a result of glycosylation, the apparent molecular mass of rmCHI3L1 is approximately 50 kDa in SDS-PAGE under reducing conditions.
Protein Length : Met1-Ala381
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 97 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : Chi3l1 chitinase 3-like 1 [ Mus musculus ]
Official Symbol : Chi3l1
Synonyms : CHI3L1; chitinase 3-like 1; chitinase-3-like protein 1; GP-39; CGP-39; cartilage glycoprotein 39; Gp39; Brp39; AW208766;
Gene ID : 12654
mRNA Refseq : NM_007695
Protein Refseq : NP_031721

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is there any other mode of action for CHI3L1? 01/05/2022

In addition to being involved in cartilage metabolism and immune regulation, CHI3L1 may also have other modes of action, such as regulating cell adhesion and migration.

What is the role of CHI3L1 in immune regulation? 07/11/2021

This protein can act as an immunomodulator to inhibit the inflammatory response and the activity of immune cells, thereby maintaining the balance of the immune system.

Does CHI3L1 involved in the metabolism and repair of cartilage? 04/15/2021

CHI3L1 can bind to receptors on the surface of chondrocytes, stimulate the proliferation and differentiation of chondrocytes, and promote cartilage synthesis and repair.

How is the expression level of CHI3L1 regulated? 03/20/2021

The expression level of CHI3L1 is regulated by a variety of factors, including transcription factors, signal transduction pathways, and epigenetic modifications.

What is the association between CHI3L1 and joint diseases such as rheumatoid arthritis? 04/26/2020

In joint diseases such as rheumatoid arthritis, the expression level of CHI3L1 may be abnormally elevated, promoting inflammation and joint damage, and aggravating the condition.

How to detect the expression level of CHI3L1? 12/16/2019

The expression level of CHI3L1 can be detected by immunohistochemistry, western blotting, and real-time PCR.

Customer Reviews (3)

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Reviews
12/15/2022

    CHI3L1 has strong biological activity combined with its high purity makes its experimental results extremely reliable.

    10/22/2022

      The band strength in Western blot was high, which improved the signal-to-noise ratio of the experiment.

      10/24/2021

        It can simplify the complex chemical reaction and improve the high yield, shorten the experimental time.

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