Recombinant Human Liver X receptor-LBD, His-tagged
Cat.No. : | NR1H2-010N |
Product Overview : | Produced by transient expression of LXR in non-transgenic plants. Recombinant human LXR contains a 6-His-tag at the N-terminal end and is purified by sequential chromatography (FPLC). Contains no animal–derived components or impurities. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NR1H2-010N |
Description : | Liver X Receptors (LXRs) are nuclear receptors that regulate the metabolism of cholesterol and bile acids. There are two subtypes of LXRs, LXRα and LXRβ. The LXRs are ligand-dependent transcription factors that form permissive heterodimers with the retinoid X receptor (RXR). LXR- member of Nuclear Receptor Family is activated by certain oxysterol derivatives of cholesterol. They play an important role in cholesterol, lipid, and carbohydrate metabolism. |
Source : | Nicotiana benthamiana |
Sequence : | HHHHHHSSGIEGRGRLIKHMTPGGS EAGSQGSGEGEGVQLTAAQELMIQQ LVAAQLQCNKRSFSDQPKVTPWPLG ADPQSRDARQQRFAHFTELAIISVQ EIVDFAKQVPGFLQLGREDQIALLK ASTIEIMLLETARRYNHETECITFL KDFTYSKDDFHRAGLQVEFINPIFE FSRAMRRLGLDDAEYALLIAINIFS ADRPNVQEPGRVEALQQPYVEALLS YTRIKRPQDQLRFPRMLMKLVSLRT LSSVHSEQVFALRLQDKKLPPLLSE IWDVHE |
Formulation : | Lyophilized from a Tris HCl 20mM buffer at pH 8, 0.1% SDS. |
Molecularformula : | C1422H2249N409O415S8 |
Extinction coefficient : | E0.1% = 0.581 (A280 nm). |
Molecular weight : | 31.9 kDa (201-461 amino acids) |
Purity : | > 97% by SDS-PAGE gel. |
Endotoxin level : | < 0.04 EU/μg protein (LAL method) |
Storage : | This lyophilized preparation is stable at 2-8º C. For long storage should be kept at -20º C and it is recommended to add a carrier protein (0.1% HSA or BSA). Repeated freezing and thawing is not recommended. |
Gene Name : | NR1H2 nuclear receptor subfamily 1, group H, member 2 [ Homo sapiens ] |
Official Symbol : | NR1H2 |
Synonyms : | NR1H2; nuclear receptor subfamily 1, group H, member 2; NER; UNR; LXRB; LXR-b; NER-I; RIP15; liver X receptor beta; liver X receptor-beta; nuclear orphan receptor LXR-beta; oxysterols receptor LXR-beta; steroid hormone-nuclear receptor NER; ubiquitously-expressed nuclear receptor; LX receptor beta |
Gene ID : | 7376 |
mRNA Refseq : | NM_007121 |
Protein Refseq : | NP_009052 |
MIM : | 600380 |
UniProt ID : | P55055 |
Chromosome Location : | 19q13.3 |
Function : | Gene Expression |
Products Types
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NR1H2-2911R | Recombinant Rhesus Macaque NR1H2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NR1H2-6180M | Recombinant Mouse NR1H2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NR1H2-1399B | Recombinant Bovine NR1H2 Protein | +Inquiry |
◆ Lysates | ||
NR1H2-440HCL | Recombinant Human NR1H2 lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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