Recombinant Human Liver X receptor-LBD, His-tagged NR1H2-010N

Recombinant Human Liver X receptor-LBD, His-tagged

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Recombinant Human Liver X receptor-LBD, His-tagged

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Cat. No. : NR1H2-010N
Product Overview : Produced by transient expression of LXR in non-transgenic plants. Recombinant human LXR contains a 6-His-tag at the N-terminal end and is purified by sequential chromatography (FPLC). Contains no animal–derived components or impurities.
Description : Liver X Receptors (LXRs) are nuclear receptors that regulate the metabolism of cholesterol and bile acids. There are two subtypes of LXRs, LXRα and LXRβ. The LXRs are ligand-dependent transcription factors that form permissive heterodimers with the retinoid X receptor (RXR). LXR- member of Nuclear Receptor Family is activated by certain oxysterol derivatives of cholesterol. They play an important role in cholesterol, lipid, and carbohydrate metabolism.
Source : Nicotiana benthamiana
Sequence : HHHHHHSSGI EGRGRLIKHM TPGGSEAGSQ GSGEGEGVQL TAAQELMIQQ LVAAQLQCNK RSFSDQPKVT PWPLGADPQS RDARQQRFAH FTELAIISVQ EIVDFAKQVP GFLQLGREDQ IALLKASTIE IMLLETARRY NHETECITFL KDFTYSKDDF HRAGLQVEFI NPIFEFSRAM RRLGLDDAEY ALLIAINIFS ADRPNVQEPG RVEALQQPYV EALLSYTRIK RPQDQLRFPR MLMKLVSLRT LSSVHSEQVF ALRLQDKKLP PLLSEIWDVH E
Formulation : Lyophilized from a Tris HCl 20mM buffer at pH 8, 0.1% SDS.
Molecularformula : C1422H2249N409O415S8
Extinction coefficient : E0.1% = 0.581 (A280 nm).
Molecular weight : 31.9 kDa (201-461 amino acids)
Purity : > 97% by SDS-PAGE gel.
Endotoxin level : < 0.04 EU/μg protein (LAL method)
Storage : This lyophilized preparation is stable at 2-8º C. For long storage should be kept at -20º C and it is recommended to add a carrier protein (0.1% HSA or BSA). Repeated freezing and thawing is not recommended.
Gene Name : NR1H2 nuclear receptor subfamily 1, group H, member 2 [ Homo sapiens ]
Official Symbol : NR1H2
Synonyms : NR1H2; nuclear receptor subfamily 1, group H, member 2; NER; UNR; LXRB; LXR-b; NER-I; RIP15; liver X receptor beta; liver X receptor-beta; nuclear orphan receptor LXR-beta; oxysterols receptor LXR-beta; steroid hormone-nuclear receptor NER; ubiquitously-expressed nuclear receptor; LX receptor beta
Gene ID : 7376
mRNA Refseq : NM_007121
Protein Refseq : NP_009052
MIM : 600380
UniProt ID : P55055
Chromosome Location : 19q13.3
Function : Gene Expression
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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