Active Recombinant Human Lectin, Galactoside-Binding, Soluble, 1
Cat.No. : | LGALS1-6976H |
Product Overview : | A DNA sequence encoding the human LGALS1 (Met 1-Asp135) was expressed. The recombinant human LGALS1 comprises 134 amino acids and migrates as an approximately 15 kDa band in SDS-PAGE under reducing conditions as predicted. |
- Specification
- Gene Information
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Description : | LGALS1, the first identified member of the β-galactoside-binding animal lectin family, and exists as a homodimer of a single carbohydrate-recognition domain. LGALS1 is expressed in a variety of cell types, including thymic epithelial cells, endothelial cells, dendritic cells, macrophages, fibroblasts, and bone marrow stromal cells. There is increased galectin-1 expression in many types of cancer, including colon, breast, ovary and prostate carcinomas. Several potential glycoprotein ligands for galectin-1 have been identified, including lysosome-associated membrane glycoproteins and fibronectin, laminin, as well as T-cell glycoproteins CD43 and CD45. |
Source : | E. coli |
Species : | Human |
Tag : | N/A |
Predicted N Terminal : | Ala 2 |
Form : | Lyophilized from 0.2μm filtered solution of PBS, 0.1Mβ-lactosyl, pH7.4. Normally 5 %-8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Bio-activity : | Measured by its ability to agglutinate human red blood cells. The ED50 for this effect is typically 0.5-3 μg/ml. |
Molecular Mass : | 15 kDa |
Protein length : | 134 aa |
Endotoxin : | < 5 eu per 1 mg of the protein as determined by the lal |
Purity : | >97 % as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70 °C. |
Storage : | Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | LGALS1 lectin, galactoside-binding, soluble, 1 [ Homo sapiens ] |
Official Symbol : | LGALS1 |
Synonyms : | LGALS1; lectin, galactoside-binding, soluble, 1; galectin-1; galectin 1; GBP; HBL; HPL; gal-1; HLBP14; galaptin; 14 kDa lectin; S-Lac lectin 1; lactose-binding lectin 1; 14 kDa laminin-binding protein; putative MAPK-activating protein PM12; beta-galactoside-binding lectin L-14-I; beta-galactoside-binding protein 14kDa; GAL1; DKFZp686E23103; |
Gene ID : | 3956 |
mRNA Refseq : | NM_002305 |
Protein Refseq : | NP_002296 |
MIM : | 150570 |
UniProt ID : | P09382 |
Chromosome Location : | 22q13.1 |
Pathway : | Validated targets of C-MYC transcriptional repression, organism-specific biosystem; |
Function : | galactoside binding; glycoprotein binding; lactose binding; laminin binding; protein homodimerization activity; signal transducer activity; sugar binding; |
Products Types
◆ Recombinant Protein | ||
Lgals1-1310M | Recombinant Mouse Lgals1 Protein, MYC/DDK-tagged | +Inquiry |
LGALS1-2321R | Recombinant Rhesus Macaque LGALS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
LGALS1-1289H | Recombinant Human LGALS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Lgals1-4007M | Active Recombinant Mouse Lgals1 protein(Met1-Glu135) | +Inquiry |
LGALS1-1989B | Recombinant Bovine LGALS1 Protein (2-135 aa), His-SUMO-tagged | +Inquiry |
◆ Lysates | ||
LGALS1-4770HCL | Recombinant Human LGALS1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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