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Active Recombinant Human Lectin, Galactoside-Binding, Soluble, 1

Cat.No. : LGALS1-6976H
Product Overview : A DNA sequence encoding the human LGALS1 (Met 1-Asp135) was expressed. The recombinant human LGALS1 comprises 134 amino acids and migrates as an approximately 15 kDa band in SDS-PAGE under reducing conditions as predicted.
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  • Gene Information
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Description : LGALS1, the first identified member of the β-galactoside-binding animal lectin family, and exists as a homodimer of a single carbohydrate-recognition domain. LGALS1 is expressed in a variety of cell types, including thymic epithelial cells, endothelial cells, dendritic cells, macrophages, fibroblasts, and bone marrow stromal cells. There is increased galectin-1 expression in many types of cancer, including colon, breast, ovary and prostate carcinomas. Several potential glycoprotein ligands for galectin-1 have been identified, including lysosome-associated membrane glycoproteins and fibronectin, laminin, as well as T-cell glycoproteins CD43 and CD45.
Source : E. coli
Species : Human
Tag : N/A
Predicted N Terminal : Ala 2
Form : Lyophilized from 0.2μm filtered solution of PBS, 0.1Mβ-lactosyl, pH7.4. Normally 5 %-8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Bio-activity : Measured by its ability to agglutinate human red blood cells. The ED50 for this effect is typically 0.5-3 μg/ml.
Molecular Mass : 15 kDa
Protein length : 134 aa
Endotoxin : < 5 eu per 1 mg of the protein as determined by the lal
Purity : >97 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70 °C.
Storage : Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name : LGALS1 lectin, galactoside-binding, soluble, 1 [ Homo sapiens ]
Official Symbol : LGALS1
Synonyms : LGALS1; lectin, galactoside-binding, soluble, 1; galectin-1; galectin 1; GBP; HBL; HPL; gal-1; HLBP14; galaptin; 14 kDa lectin; S-Lac lectin 1; lactose-binding lectin 1; 14 kDa laminin-binding protein; putative MAPK-activating protein PM12; beta-galactoside-binding lectin L-14-I; beta-galactoside-binding protein 14kDa; GAL1; DKFZp686E23103;
Gene ID : 3956
mRNA Refseq : NM_002305
Protein Refseq : NP_002296
MIM : 150570
UniProt ID : P09382
Chromosome Location : 22q13.1
Pathway : Validated targets of C-MYC transcriptional repression, organism-specific biosystem;
Function : galactoside binding; glycoprotein binding; lactose binding; laminin binding; protein homodimerization activity; signal transducer activity; sugar binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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