Recombinant Human CALM1

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Recombinant Human CALM1

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Cat. No. : CALM1-90H
Description : The human Calmodulin 1 full-lengthrecombinant protein was expressed in E. coli.
Introduction : Calmodulin 1 is a member of calcium-modulated proteins, which is present in the cytosol and on membranes facing the cytosol, and has a high affinity for calcium. Calmodulin 1 has 4 calcium-binding domains and plays a role in cell growth, cell cycle, signal transduction, and the synthesis and release of neurotransmitters. Calmodulin can bind to the epidermal growth factor receptor at its cytosolic juxtamembrane region and this inhibits its tyrosine kinase activity. A number of other proteins including HSP70 have been shown to interact with Calmodulin 1 in a cell-phase-specific manner.
AA Sequence : MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAK
Source : E. coli
Molecular weight : 16kDa
Formulation : Liquid, in 20 mMTris, pH 7.5
Stability : Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C. Aliquot to avoid repeated freezing and thawing.
Purification : Conventional Chromatography
Concentration : 1 mg/ml
Purity : > 90% as determined by SDS-PAGE.
SDS PAGE : Loading 3 ug protein in 15% SDS-PAGE
Gene Name : CALM1 calmodulin 1 (phosphorylase kinase, delta) [ Homo sapiens ]
Official Symbol : CALM1
Synonyms : CALM1; calmodulin 1 (phosphorylase kinase, delta); CAMI; PHKD; DD132; CALML2; calmodulin 1; phosphorylase kinase, delta subunit; EC 2.7.11.19; CALMCAM; CAM1; CAM2; CAM3; CAMB; CAMC; CAMIII; CaM
Gene ID : 801
mRNA Refseq : NM_006888
Protein Refseq : NP_008819
MIM : 114180
UniProt ID : P62158
Chromosome Location : 14q24-q31
Pathway : Alzheimer"s disease; Calcium signaling pathway; Glioma; GnRH signaling pathway; Insulin signaling pathway; Long-term potentiation; Melanogenesis; Neurotrophin signaling pathway; Olfactory transduction; Phosphatidylinositol signaling system; Vascular smooth muscle contraction
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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