"NDUFS4" Related Products

Recombinant Human NADH Dehydrogenase (ubiquinone) Fe-S Protein 4, 18kDa (NADH-coenzyme Q reductase)

Cat.No.: NDUFS4-2509H
Product Overview: Recombinant human NDUFS4 protein was expressed in E. coli and purified by using conventional chromatography. MW: 15.5 kDa.
Description: NDUFS4 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone.
Source: E. coli
Species: Human
Tag: N/A
Form: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 30% glycerol.
Molecular Mass: 15.5 kDa (134aa), confirmed by MALDI-TOF.
Protein length: 43-175aa
AA Sequence: MAQDQTQDTQ LITVDEKLDI TTLTGVPEEH IKTRKVRIFV PARNNMQSGV NNTKKWKMEF DTRERWENPL MGWASTADPL SNMVLTFSTK EDAVSFAEKN GWSYDIEERK VPKPKSKSYG ANFSWNKRTR VSTK
Purity: >90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml (determined by Bradford assay)
Gene Name: NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) [ Homo sapiens ]
Official Symbol: NDUFS4
Synonyms: NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase); NADH dehydrogenase (ubiquinone) Fe S protein 4 (18kD) (NADH coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial; AQDQ; CI 18; complex I 18kDa subunit; CI-AQDQ; CI-18 kDa; complex I-AQDQ; complex I-18 kDa; NADH-coenzyme Q reductase, 18-KD; NADH-ubiquinone oxidoreductase 18 kDa subunit; NADH dehydrogenase (ubiquinone) iron-sulfur protein 4; mitochondrial respiratory chain complex I (18-KD subunit); CI-18;
Gene ID: 4724
mRNA Refseq: NM_002495
Protein Refseq: NP_002486
MIM: 602694
UniProt ID: O43181
Chromosome Location: 5q11.1
Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Electron Transport Chain, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;
Function: NADH dehydrogenase (ubiquinone) activity; contributes_to NADH dehydrogenase (ubiquinone) activity; oxidoreductase activity, acting on NADH or NADPH;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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