Recombinant Human Proteasome (prosome, macropain) Assembly Chaperone 2, His-tagged

• Cat.No.: PSMG2-6863H
• Product Overview: Recombinant human PSMG2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. MW: 31.8 kDa.

Specification

• Description: PSMG2, also known as proteasome assembly chaperone 2, promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.1M NaCl.
• Molecular Mass: 31.8 kDa (287aa), confirmed by MALDI-TOF.
• Protein length: 1-264aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMFVPCGE SAPDLAGFTL LMPAVSVGNV GQLAMDLIIS TLNMSKIGYF YTDCLVPMVG NNPYATTEGN STELSINAEV YSLPSRKLVA LQLRSIFIKY KSKPFCEKLL SWVKSSGCAR VIVLSSSHSY QRNDLQLRST PFRYLLTPSM QKSVQNKIKS LNWEEMEKSR CIPEIDDSEF CIRIPGGGIT KTLYDESCSK EIQMAVLLKF VSEGDNIPDA LGLVEYLNEW LQILKPLSDD PTVSASRWKI PSSWRLLFGS GLPPALF
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: PSMG2 proteasome (prosome, macropain) assembly chaperone 2 [ Homo sapiens ]
• Official Symbol: PSMG2
• Synonyms: PSMG2; proteasome (prosome, macropain) assembly chaperone 2; PAC2; HCCA3; CLAST3; MDS003; HsT1707; TNFSF5IP1; proteasome assembly chaperone 2; PAC-2; HSPC260; HDCMC29P; x 003 protein; proteasome assembling chaperone 2; CD40 ligand-activated specific transcript 3; hepatocellular carcinoma susceptibility protein; hepatocellular carcinoma-susceptibility protein 3; tumor necrosis factor superfamily member 5-induced protein 1; tumor necrosis factor superfamily, member 5-induced protein 1; likely ortholog of mouse CD40 ligand-activated specific transcript 3 (Clast3); MGC15092; proteasome assembly chaperone 2
• Gene ID: 56984
• mRNA Refseq: NM_020232
• Protein Refseq: NP_064617
• MIM: 609702
• UniProt ID: Q969U7
• Chromosome Location: 18p11.21
• Function: protein binding