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Recombinant Human Muted Homolog (mouse), His-tagged

Cat.No. : MUTED-6946H
Product Overview : Recombinant human MUTED protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
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Description : MUTED is involved in the development of lysosome related organelles, such as melanosomes and platelet dense granules. MUTED interacts with pallidin, dystrobrevin binding protein 1 and CNO/cappuccino. It is part of the biogenesis of lysosome related organelles complex 1 (BLOC1). Also, MUTED is ubiquitously expressed with higher levels in brain, bone marrow, kidney, and liver and lower levels in skeletal muscle.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 40% glycerol,2mM DTT, 0.1mM PMSF, 1mM EDTA.
Molecular Mass : 24 kDa (210aa), confirmed by MALDI-TOF
Protein length : 1-187aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMSGGGTE TPVGCEAAPG GGSKKRDSLG TAGSAHLIIK DLGEIHSRLL DHRPVIQGET RYFVKEFEEK RGLREMRVLE NLKNMIHETN EHTLPKCRDT MRDSLSQVLQ RLQAANDSVC RLQQREQERK KIHSDHLVAS EKQHMLQWDN FMKEQPNKRA EVDEEHRKAM ERLKEQYAEM EKDLAKFSTF
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/ml (determined by Bradford assay)
Gene Name : MUTED muted homolog (mouse) [ Homo sapiens ]
Official Symbol : MUTED
Synonyms : MUTED; muted homolog (mouse); protein Muted homolog; dJ303A1.3; MU; FLJ18427; DKFZp686E2287;
Gene ID : 63915
mRNA Refseq : NM_001199322
Protein Refseq : NP_001186251
MIM : 607289
UniProt ID : Q8TDH9
Chromosome Location : 6p25.1-p24.3
Pathway : Clathrin derived vesicle budding, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Lysosome Vesicle Biogenesis, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; trans-Golgi Network Vesicle Budding, organism-specific biosystem;
Function : protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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