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Recombinant Human POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3, His-tagged

Cat.No. : POLR2J3-7175H
Product Overview : Recombinant human POLR2J3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 15.5 kDa.
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  • Gene Information
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Description : DNA-directed RNA polymerase II subunit RPB11-b2, also known as POLR2J3, belongs to the eukaryotic RPB11 RNA polymerase subunit family. POLR2J (DNA-directed RNA polymerase II subunit J) exist as three variants POLR2J1 (RPB11-a), POLR2J2 (RPB11-b1), and POLR2J3 (RPB11-b2). POLR2J3 is DNA-dependent RNA polymerases that catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol,1mM DTT.
Molecular Mass : 15.5 kDa (138aa) confirmed by MALDI-TOF
Protein length : 1-115aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMNAPPAF ESFLLFEGEK ITINKDTKVP NACLFTINKE DHTLGNIIKS QLLKDPQVLF AGYKVPHPLE HKIIIRVQTT PDYSPQEAFT NAITDLISEL SLLEERFRTC LLPLRLLP
Purity : >95% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Name : POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 [ Homo sapiens ]
Official Symbol : POLR2J3
Synonyms : POLR2J3; polymerase (RNA) II (DNA directed) polypeptide J3; POLR2J2; RPB11b1; RPB11b2; DNA-directed RNA polymerase II subunit RPB11-b2; RNA polymerase II subunit B11-b2; DNA-directed RNA polymerase II subunit 11; DNA-directed RNA polymerase II subunit J3
Gene ID : 548644
mRNA Refseq : NM_001097615
Protein Refseq : NP_001091084
UniProt ID : Q9GZM3
Chromosome Location : 7q22.1
Pathway : Epstein-Barr virus infection, organism-specific biosystem; Huntington"s disease, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Pyrimidine metabolism, organism-specific biosystem; RNA polymerase, organism-specific biosystem
Function : DNA binding; DNA-directed RNA polymerase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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