Recombinant Human Polymerase (RNA) III (DNA Sirected) Polypeptide H (22.9kD), His-tagged
Cat.No. : | POLR3H-7187H |
Product Overview : | Recombinant human POLR3H protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 25.3kDa. |
- Specification
- Gene Information
- Related Products
Description : | POLR3H, also as known as A1665 and RPC8, belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family. POLR3H is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. POLR3H acts as nuclear and cytosolic DNA sensor involved in innate immune response. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT. |
Molecular Mass : | 25.3kDa (227aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher) |
Protein length : | 1-204aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMFVLVEM VDTVRIPPWQ FERKLNDSIA EELNKKLANK VVYNVGLCIC LFDITKLEDA YVFPGDGASH TKVHFRCVVF HPFLDEILIG KIKGCSPEGV HVSLGFFDDI LIPPESLQQP AKFDEAEQVW VWEYETEEGA HDLYMDTGEE IRFRVVDESF VDTSPTGPSS ADATTSSEEL PKKEAPYTLV GSISEPGLGL LSWWTSN |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) [ Homo sapiens ] |
Official Symbol : | POLR3H |
Synonyms : | POLR3H; polymerase (RNA) III (DNA directed) polypeptide H (22.9kD); DNA-directed RNA polymerase III subunit RPC8; KIAA1665; RPC8; RNA polymerase III subunit C8; RNA polymerase III subunit RPC8; DNA-directed RNA polymerase III subunit H; RNA nucleotidyltransferase (DNA-directed); RNA polymerase III subunit 22.9 kDa subunit; DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide; RPC22.9; MGC29654; MGC111097; |
Gene ID : | 171568 |
mRNA Refseq : | NM_001018050 |
Protein Refseq : | NP_001018060 |
UniProt ID : | Q9Y535 |
Chromosome Location : | 22q13 |
Pathway : | Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Epstein-Barr virus infection, organism-specific biosystem; Epstein-Barr virus infection, conserved biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem; Gene Expression, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; |
Function : | DNA binding; DNA-directed RNA polymerase activity; |
Products Types
◆ Recombinant Protein | ||
POLR3H-6934M | Recombinant Mouse POLR3H Protein, His (Fc)-Avi-tagged | +Inquiry |
Polr3h-5008M | Recombinant Mouse Polr3h Protein, Myc/DDK-tagged | +Inquiry |
POLR3H-3341R | Recombinant Rhesus Macaque POLR3H Protein, His (Fc)-Avi-tagged | +Inquiry |
POLR3H-1732H | Recombinant Human POLR3H Protein, His (Fc)-Avi-tagged | +Inquiry |
POLR3H-4788C | Recombinant Chicken POLR3H | +Inquiry |
◆ Lysates | ||
POLR3H-3021HCL | Recombinant Human POLR3H 293 Cell Lysate | +Inquiry |
POLR3H-3022HCL | Recombinant Human POLR3H 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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