Recombinant Mouse Lectin, Galactoside-Binding, Soluble, 1, His-tagged

• Cat.No.: LGALS1-7210M
• Product Overview: Recombinant mouse LGALS1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 17 kDa.

Specification

• Description: LGALS1 is a member of the beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This protein is an autocrine negative growth factor that regulates cell proliferation. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes, thus LGALS1 has immunosuppressive and anti-inflammatory properties. LGALS1 also regulates tumor angiogenesis and is a target for angiostatic cancer therapy.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol.
• Molecular Mass: 17 kDa (159aa), confirmed by MALDI-TOF
• Protein length: 1-135aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMACGLV ASNLNLKPGE CLKVRGEVAS DAKSFVLNLG KDSNNLCLHF NPRFNAHGDA NTIVCNTKED GTWGTEHREP AFPFQPGSIT EVCITFDQAD LTIKLPDGHE FKFPNRLNME AINYMAADGD FKIKCVAFE
• Purity: >95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: Lgals1 lectin, galactose binding, soluble 1 [ Mus musculus ]
• Official Symbol: LGALS1
• Synonyms: LGALS1; lectin, galactose binding, soluble 1; galectin-1; galaptin; 14 kDa lectin; S-Lac lectin 1; lactose-binding lectin 1; beta-galactoside binding protein; lectin galactoside-binding soluble 1; beta-galactoside-binding lectin L-14-I; L14; Gal-1; Galbp; L-14.5; Lect14; AA410090
• Gene ID: 16852
• mRNA Refseq: NM_008495
• Protein Refseq: NP_032521
• Function: galactose binding; galactoside binding; glycoprotein binding; lactose binding; laminin binding; protein homodimerization activity; signal transducer activity; sugar binding