Active Recombinant Human PIK3C2A, GST-tagged
Cat.No. : | PIK3C2A-1452H |
Product Overview : | Recombinant human PIK3C2A (299-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | PIK3C2A is belongs to the phosphoinositide 3-kinase (PI3K) family which play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2A can phosphorylate phosphatidylinositol and phosphatidylinositol-4-phosphate in vitro. PIK3C2A contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 22 nmol/min/mg |
Molecular Mass : | ~155 kDa |
Protein length : | 299 aa-end |
Purity : | >70% |
Applications : | Kinase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | PIK3C2A phosphoinositide-3-kinase, class 2, alpha polypeptide [ Homo sapiens ] |
Official Symbol : | PIK3C2A |
Synonyms : | PIK3C2A; phosphoinositide-3-kinase, class 2, alpha polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha; PI3K C2alpha; PI3K-C2alpha; PI3K-C2-alpha; ptdIns-3-kinase C2 subunit alpha; phosphoinositide 3-kinase-C2-alpha; C2-containing phosphatidylinositol kinase; CPK; PI3-K-C2A; MGC142218; PI3-K-C2(ALPHA); DKFZp686L193; |
Gene ID : | 5286 |
mRNA Refseq : | NM_002645 |
Protein Refseq : | NP_002636 |
MIM : | 603601 |
UniProt ID : | O00443 |
Chromosome Location : | 11p15.5-p14 |
Pathway : | 3-phosphoinositide biosynthesis, organism-specific biosystem; 3-phosphoinositide biosynthesis, conserved biosystem; Clathrin derived vesicle budding, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Insulin Signaling, organism-specific biosystem; |
Function : | 1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; binding; nucleotide binding; phosphatidylinositol 3-kinase activity; phosphatidylinositol binding; phosphotransferase activity, alcohol group as acceptor; |
Products Types
◆ Recombinant Protein | ||
PIK3C2A-551H | Recombinant Human PIK3C2A Protein, His-tagged | +Inquiry |
PIK3C2A-3165H | Recombinant Human PIK3C2A Protein (Phe172-Asn403), His tagged | +Inquiry |
PIK3C2A-1715H | Recombinant Human PIK3C2A, His-tagged | +Inquiry |
Pik3c2a-552M | Recombinant Mouse Pik3c2a Protein, His/GST-tagged | +Inquiry |
PIK3C2A-191H | Active Recombinant Human PIK3C2A(299-end) Protein, N-His-tagged | +Inquiry |
◆ Lysates | ||
PIK3C2A-3191HCL | Recombinant Human PIK3C2A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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