"PIM2" Related Products

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Recombinant Human PIM2 (Active), GST-tagged

Cat.No.: PIM2-1456H
Product Overview: Recombinant full-length human PIM2 was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Description: PIM2 is a serine threonine kinase that is present in all tissues, being most abundant in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. It is highly expressed in human leukemic, lymphoma and colorectal adenocarcinoma cell lines. This suggests a role for PIM2 in proliferating cells as well as during meiosis. Similar to PIM1, PIM2 also acts as a pro-survival kinase and BAD protein is a legitimate PIM2 substrate.
Source: Sf9 Cells
Species: Human
Tag: GST
Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Bio-activity: 305 nmol/min/mg
Molecular Mass: ~61 kDa
Protein length: Full length
Purity: >95%
Applications: Kinase Assay, Western Blot
Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration: 0.1μg/μl
Gene Name: PIM2 pim-2 oncogene [ Homo sapiens ]
Official Symbol: PIM2
Synonyms: PIM2; pim-2 oncogene; serine/threonine-protein kinase pim-2; pim-2h; serine/threonine protein kinase pim-2; proto-oncogene Pim-2 (serine threonine kinase);
Gene ID: 11040
mRNA Refseq: NM_006875
Protein Refseq: NP_006866
MIM: 300295
UniProt ID: Q9P1W9
Chromosome Location: Xp11.23
Pathway: Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem;
Function: ATP binding; nucleotide binding; protein serine/threonine kinase activity;

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