Recombinant Human STK39 (Active), His-tagged

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Recombinant Human STK39 (Active), His-tagged

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Cat.No. : STK39-1490H
Product Overview : Recombinant full-length human STK39 (STLK3) was expressed using baculovirus in Sf9 insect cells using an N-terminal His tag.
Description : STK39 (also known as serine threonine kinase 39) is involved in the cellular stress response pathway. STK39 is activated in response to hypotonic stress leading to phosphorylation of several cation-chloride-coupled co-transporters. STK39 activates the p38 MAP kinase pathway and its interaction with p38 decreases during cellular stress. STK39 acts as an intermediate in the response to cellular stress. STK39 is also an independent risk factor for hypertension in men and its intragenic SNPs can interact and function in the control of blood pressure.
Source : Sf9 Cells
Species : Human
Tag : His
Form : Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Bio-activity : 22 nmol/min/mg
Molecular Mass : ~63 kDa
Protein length : Full length
Purity : >95%
Applications : Kinase Assay, Western Blot
Storage : Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration : 0.1μg/μl
Gene Name : STK39 serine threonine kinase 39 [ Homo sapiens ]
Official Symbol : STK39
Synonyms : STK39; serine threonine kinase 39; STE20/SPS1-related proline-alanine-rich protein kinase; DCHT; SPAK; STE20/SPS1 homolog (yeast); STE20/SPS1 homolog; ste-20-related kinase; Ste20-like protein kinase; small intestine SPAK-like kinase; serine/threonine-protein kinase 39; proline-alanine-rich STE20-related kinase; serine threonine kinase 39 (STE20/SPS1 homolog, yeast); PASK; DKFZp686K05124;
Gene ID : 27347
mRNA Refseq : NM_013233
Protein Refseq : NP_037365
MIM : 607648
UniProt ID : Q9UEW8
Chromosome Location : 2q24.3
Pathway : T Cell Receptor Signaling Pathway, organism-specific biosystem; TCR signaling in naive CD4+ T cells, organism-specific biosystem;
Function : ATP binding; nucleotide binding; protein kinase binding; receptor signaling protein serine/threonine kinase activity;

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