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Active Recombinant Human TEC, GST-tagged

Cat.No. : NR4A3-1494H
Product Overview : Full-length recombinant human TEC was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
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  • Gene Information
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Description : TEC is a member of the Tec family of non-receptor protein-tyrosine kinases that are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. TEC is an integral component of T cell signaling and has a distinct role in T cell activation. Defects in TEC may be associated with myelodysplastic syndrome. TEC plays a crucial role in regulating FGF2 secretion under various physiological conditions and it inhibits CD25 expression in human T-lymphocyte.
Source : Sf9 Cells
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 10 nmol/min/mg
Molecular Mass : ~103 kDa
Protein length : Full length
Purity : >75%
Applications : Kinase Assay, Western Blot
Storage : Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration : 0.1μg/μl
Gene Name : NR4A3 nuclear receptor subfamily 4, group A, member 3 [ Homo sapiens ]
Official Symbol : NR4A3
Synonyms : NR4A3; nuclear receptor subfamily 4, group A, member 3; nuclear receptor subfamily 4 group A member 3; CHN; CSMF; MINOR; NOR1; nuclear hormone receptor NOR-1; neuron-derived orphan receptor 1; mitogen-induced nuclear orphan receptor; translocated in extraskeletal chondrosarcoma; chondrosarcoma, extraskeletal myxoid, fused to EWS; TEC;
Gene ID : 8013
mRNA Refseq : NM_006981
Protein Refseq : NP_008912
MIM : 600542
UniProt ID : Q92570
Chromosome Location : 9q22
Pathway : Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Hypertrophy Model, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;
Function : DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; binding; metal ion binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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