"NR4A3" Related Products


Recombinant Human TEC (Active), GST-tagged

Cat.No. : NR4A3-1494H
Product Overview : Full-length recombinant human TEC was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : TEC is a member of the Tec family of non-receptor protein-tyrosine kinases that are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. TEC is an integral component of T cell signaling and has a distinct role in T cell activation. Defects in TEC may be associated with myelodysplastic syndrome. TEC plays a crucial role in regulating FGF2 secretion under various physiological conditions and it inhibits CD25 expression in human T-lymphocyte.
Source : Sf9 Cells
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 10 nmol/min/mg
Molecular Mass : ~103 kDa
Protein length : Full length
Purity : >75%
Applications : Kinase Assay, Western Blot
Storage : Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration : 0.1μg/μl
Gene Name : NR4A3 nuclear receptor subfamily 4, group A, member 3 [ Homo sapiens ]
Official Symbol : NR4A3
Synonyms : NR4A3; nuclear receptor subfamily 4, group A, member 3; nuclear receptor subfamily 4 group A member 3; CHN; CSMF; MINOR; NOR1; nuclear hormone receptor NOR-1; neuron-derived orphan receptor 1; mitogen-induced nuclear orphan receptor; translocated in extraskeletal chondrosarcoma; chondrosarcoma, extraskeletal myxoid, fused to EWS; TEC;
Gene ID : 8013
mRNA Refseq : NM_006981
Protein Refseq : NP_008912
MIM : 600542
UniProt ID : Q92570
Chromosome Location : 9q22
Pathway : Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Hypertrophy Model, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;
Function : DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; binding; metal ion binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding;

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