Active Recombinant Human PTPN11, GST-tagged
Cat.No. : | PTPN11-1518H |
Product Overview : | Recombinant human PTPN11 (246-593) was expressed in E.coli cells using a N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | Mammalian PTPases can be subdivided into 1 of 2 broad categories: transmembrane receptor PTPases and intracellular PTPases. PTPN11 is one of the 2 closely related mammalian intracellular PTPases whose sequences encode 2 tandem SRC homology 2 (SH2) domains that are located at the amino-terminal side of a single PTPase catalytic domain. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 20 mM MOPS, pH 7.5, 50 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, 30% glycerol. |
Bio-activity : | 597 nmol/min/mg |
Molecular Mass : | ~69 kDa |
Protein length : | 246-593 aa |
Purity : | >90% |
Applications : | Phosphatase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | PTPN11 protein tyrosine phosphatase, non-receptor type 11 [ Homo sapiens ] |
Official Symbol : | PTPN11 |
Synonyms : | PTPN11; protein tyrosine phosphatase, non-receptor type 11; Noonan syndrome 1 , NS1; tyrosine-protein phosphatase non-receptor type 11; BPTP3; PTP2C; SH PTP2; SHP 2; SHP2; PTP-2C; protein tyrosine phosphatase-2; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; CFC; NS1; PTP-1D; SH-PTP2; SH-PTP3; MGC14433; |
Gene ID : | 5781 |
mRNA Refseq : | NM_002834 |
Protein Refseq : | NP_002825 |
MIM : | 176876 |
UniProt ID : | Q06124 |
Chromosome Location : | 12q24.1 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Axon guidance, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CTLA4 inhibitory signaling, organism-specific biosystem; |
Function : | hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity; non-membrane spanning protein tyrosine phosphatase activity; protein binding; protein tyrosine phosphatase activity; |
Products Types
◆ Recombinant Protein | ||
Ptpn11-5235M | Recombinant Mouse Ptpn11 Protein, Myc/DDK-tagged | +Inquiry |
PTPN11-4489R | Recombinant Rat PTPN11 Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPN11-04H | Active Recombinant Human PTPN11 Protein(Full length), N-GST-tagged | +Inquiry |
Ptpn11-8674M | Active Recombinant Mouse Ptpn11 protein(Met1-Arg593), His-tagged | +Inquiry |
PTPN11-3522R | Recombinant Rhesus Macaque PTPN11 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PTPN11-1334MCL | Recombinant Mouse PTPN11 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket