"PTPN2" Related Products


Recombinant Human PTPN2 (Active), GST-tagged

Cat.No. : PTPN2-1519H
Product Overview : Recombinant full length human PTPN2 was expressed in E. coli cells using a N-terminal GST tag.
Description : Protein tyrosine phosphatase, non-receptor type 2 (PTPN2), is one of the most abundant mammalian tyrosine phosphatase. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. By virtue of protein tyrosine phosphatase activity, PTPN2 is known to be a signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation involved in cell communication and signal transduction.
Source : E. coli
Species : Human
Tag : GST
Form : Recombinant protein stored in 20 mM MOPS, pH 7.5, 50 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, 30% glycerol.
Bio-activity : 8150 nmol/min/mg
Molecular Mass : ~69 kDa
Protein length : Full length
Purity : >85%
Applications : Phosphatase Assay, Western Blot
Storage : Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration : 0.1μg/μl
Gene Name : PTPN2 protein tyrosine phosphatase, non-receptor type 2 [ Homo sapiens ]
Official Symbol : PTPN2
Synonyms : PTPN2; protein tyrosine phosphatase, non-receptor type 2; PTPT; tyrosine-protein phosphatase non-receptor type 2; TC PTP; TCELLPTP; TCPTP; T-cell protein tyrosine phosphatase; PTN2; TC-PTP;
Gene ID : 5771
mRNA Refseq : NM_001207013
Protein Refseq : NP_001193942
MIM : 176887
UniProt ID : P17706
Chromosome Location : 18p11.3-p11.2
Pathway : Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon gamma signaling, organism-specific biosystem; Regulation of IFNG signaling, organism-specific biosystem;
Function : hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity; protein binding; protein tyrosine phosphatase activity; protein tyrosine phosphatase activity; receptor activity;

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