"PTPN2" Related Products


Recombinant Human PTPN2 (Active), GST-tagged

Cat.No.: PTPN2-1519H
Product Overview: Recombinant full length human PTPN2 was expressed in E. coli cells using a N-terminal GST tag.
Description: Protein tyrosine phosphatase, non-receptor type 2 (PTPN2), is one of the most abundant mammalian tyrosine phosphatase. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. By virtue of protein tyrosine phosphatase activity, PTPN2 is known to be a signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation involved in cell communication and signal transduction.
Source: E. coli
Species: Human
Tag: GST
Form: Recombinant protein stored in 20 mM MOPS, pH 7.5, 50 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, 30% glycerol.
Bio-activity: 8150 nmol/min/mg
Molecular Mass: ~69 kDa
Protein length: Full length
Purity: >85%
Applications: Phosphatase Assay, Western Blot
Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration: 0.1μg/μl
Gene Name: PTPN2 protein tyrosine phosphatase, non-receptor type 2 [ Homo sapiens ]
Official Symbol: PTPN2
Synonyms: PTPN2; protein tyrosine phosphatase, non-receptor type 2; PTPT; tyrosine-protein phosphatase non-receptor type 2; TC PTP; TCELLPTP; TCPTP; T-cell protein tyrosine phosphatase; PTN2; TC-PTP;
Gene ID: 5771
mRNA Refseq: NM_001207013
Protein Refseq: NP_001193942
MIM: 176887
UniProt ID: P17706
Chromosome Location: 18p11.3-p11.2
Pathway: Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon gamma signaling, organism-specific biosystem; Regulation of IFNG signaling, organism-specific biosystem;
Function: hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity; protein binding; protein tyrosine phosphatase activity; protein tyrosine phosphatase activity; receptor activity;

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