Active Recombinant Human PTPRE, GST-tagged
Cat.No. : | PTPRE-1523H |
Product Overview : | Recombinant human PTPRE (75-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | PTPRE or protein tyrosine phosphatase receptor type E is a member of the protein tyrosine phosphatase (PTP) family. This family of proteins are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRE is highly expressed in brain and testis. The regulatory roles of this PTP in Ras related signal transduction pathways, cytokines induced signaling, as well as the activation of voltage-gated K+ channels have been identified. PTPRE has a transmembrane segment and a cytoplasmic region containing duplicated PTPase domains. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 8,600 nmol/min/mg |
Molecular Mass : | ~91 kDa |
Protein length : | 75 aa-end |
Purity : | >95% |
Applications : | Phosphatase Assay, Western Blot |
Storage : | Store at–70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | PTPRE protein tyrosine phosphatase, receptor type, E [ Homo sapiens ] |
Official Symbol : | PTPRE |
Synonyms : | PTPRE; protein tyrosine phosphatase, receptor type, E; receptor-type tyrosine-protein phosphatase epsilon; PTPE; protein tyrosine phosphatase, receptor type, epsilon polypeptide; HPTPE; FLJ57799; FLJ58245; R-PTP-EPSILON; DKFZp313F1310; |
Gene ID : | 5791 |
mRNA Refseq : | NM_006504 |
Protein Refseq : | NP_006495 |
MIM : | 600926 |
UniProt ID : | P23469 |
Chromosome Location : | 10q26 |
Function : | hydrolase activity; protein binding; protein homodimerization activity; protein tyrosine phosphatase activity; receptor activity; transmembrane receptor protein tyrosine phosphatase activity; |
Products Types
◆ Recombinant Protein | ||
PTPRE-4498R | Recombinant Rat PTPRE Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPRE-7285M | Recombinant Mouse PTPRE Protein, His (Fc)-Avi-tagged | +Inquiry |
Ptpre-5245M | Recombinant Mouse Ptpre Protein, Myc/DDK-tagged | +Inquiry |
PTPRE-4839R | Recombinant Rat PTPRE Protein | +Inquiry |
PTPRE-2061H | Recombinant Human PTPRE, His-tagged | +Inquiry |
◆ Lysates | ||
PTPRE-2676HCL | Recombinant Human PTPRE 293 Cell Lysate | +Inquiry |
PTPRE-2677HCL | Recombinant Human PTPRE 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionPTPRE protein acts as a phosphatase, dephosphorylating specific substrates involved in cell signaling, thereby modulating various cellular processes.
Breast cancer, colorectal cancer, and prostate cancer are among the malignancies in which PTPRE protein dysregulation has been implicated.
PTPRE protein plays a role in synaptic plasticity and neuronal development, and its dysregulation has been implicated in neurodegenerative diseases.
While PTPRE inhibitors may have off-target effects, research is focused on developing selective inhibitors to minimize potential adverse effects.
Clinical trials evaluating the efficacy of PTPRE inhibitors in cancer therapy are currently underway, with promising early results.
Customer Reviews (3)
Write a reviewWhether utilized in protein-protein interaction studies or enzymatic assays, this protein exhibits robust performance, enabling accurate data generation and analysis.
the PTPRE protein has demonstrated its efficacy in protein electron microscopy structure analysis.
This cutting-edge technique allows for the visualization and characterization of protein structures at the atomic level, providing insights into their function and potential therapeutic targets.
Ask a Question for All PTPRE Products
Required fields are marked with *
My Review for All PTPRE Products
Required fields are marked with *
Inquiry Basket