Active Recombinant Human PTPRF, GST-tagged
Cat.No. : | PTPRF-1524H |
Product Overview : | Recombinant human PTPRF (1275-1897) was expressed in E. coli cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | PTPRF or LAR is a member of the protein tyrosine phosphatase family with an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains. PTPRF has been shown to function in the regulation of epithelial cell-cell contacts at adherents junctions as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 454 nmol/min/mg |
Molecular Mass : | ~93 kDa |
Protein length : | 1275-1897 aa |
Purity : | >90% |
Applications : | Phosphatase Assay, Western Blot |
Storage : | Store at–70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | PTPRF protein tyrosine phosphatase, receptor type, F [ Homo sapiens ] |
Official Symbol : | PTPRF |
Synonyms : | PTPRF; protein tyrosine phosphatase, receptor type, F; LAR; receptor-type tyrosine-protein phosphatase F; LCA-homolog; leukocyte common antigen related; leukocyte antigen-related (LAR) PTP receptor; leukocyte antigen-related tyrosine phosphatase; receptor-linked protein-tyrosine phosphatase LAR; protein tyrosine phosphatase, receptor type, F polypeptide; FLJ43335; FLJ45062; FLJ45567; |
Gene ID : | 5792 |
mRNA Refseq : | NM_002840 |
Protein Refseq : | NP_002831 |
MIM : | 179590 |
UniProt ID : | P10586 |
Chromosome Location : | 1p34 |
Pathway : | Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Insulin Signaling, organism-specific biosystem; Insulin signaling pathway, organism-specific biosystem; Insulin signaling pathway, conserved biosystem; |
Function : | hydrolase activity; insulin receptor binding; phosphate ion binding; protein tyrosine phosphatase activity; receptor activity; receptor tyrosine kinase binding; transmembrane receptor protein tyrosine phosphatase activity; |
Products Types
◆ Recombinant Protein | ||
PTPRF-463H | Recombinant Human PTPRF Protein, His-tagged | +Inquiry |
PTPRF-4499R | Recombinant Rat PTPRF Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPRF-7286M | Recombinant Mouse PTPRF Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPRF-6106H | Recombinant Human PTPRF Protein (Asp30-Tyr224), His tagged | +Inquiry |
PTPRF-13696M | Recombinant Mouse PTPRF Protein | +Inquiry |
◆ Lysates | ||
PTPRF-1439HCL | Recombinant Human PTPRF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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