"CDK7" Related Products

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Recombinant Human CDK7, Unactive, GST-tagged

Cat.No.: CDK7-1539H
Product Overview: Recombinant full-length human CDK7 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tags.
Description: CDK7 gene is a member of the cyclin-dependent protein kinase family that is important regulators of cell cycle progression. CDK7 forms a trimeric complex with cyclin H and MAT1, which functions as a CDK-activating kinase (CAK). CDK7 is an essential component of the transcription factor TFIIH that is involved in transcription initiation and DNA repair. CDK7 is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Source: Sf9 Cells
Species: Human
Tag: GST
Form: Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Molecular Mass: ~66 kDa
Protein length: Full length
Purity: >95%
Applications: Kinase Assay, Western Blot
Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration: 0.1μg/μl
Gene Name: CDK7 cyclin-dependent kinase 7 [ Homo sapiens ]
Official Symbol: CDK7
Synonyms: CDK7; cyclin-dependent kinase 7; cyclin dependent kinase 7 (homolog of Xenopus MO15 cdk activating kinase) , cyclin dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk activating kinase); CAK; CAK1; CDKN7; MO15; STK1; p39 Mo15; protein kinase; 39 KDa protein kinase; kinase subunit of CAK; CDK-activating kinase 1; serine/threonine kinase stk1; cell division protein kinase 7; serine/threonine protein kinase 1; serine/threonine-protein kinase 1; serine/threonine protein kinase MO15; homolog of Xenopus MO15 Cdk-activating kinase; TFIIH basal transcription factor complex kinase subunit; cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase); HCAK; p39MO15;
Gene ID: 1022
mRNA Refseq: NM_001799
Protein Refseq: NP_001790
MIM: 601955
UniProt ID: P50613
Chromosome Location: 5q12.1
Pathway: Androgen Receptor Signaling Pathway, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem;
Function: ATP binding; DNA-dependent ATPase activity; RNA polymerase II carboxy-terminal domain kinase activity; androgen receptor binding; cyclin-dependent protein kinase activity; nucleotide binding; protein C-terminus binding; protein complex binding; protein kinase activity; transcription coactivator activity;

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