"KAT8" Related Products

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Recombinant Human KAT8 , GST-tagged

Cat.No.: KAT8-6957H
Product Overview: Recombinant human KAT8 (2-467; contains the catalytic domain) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: KAT8 (MYST1) or MYST histone acetyltransferase 1 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein which play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. MYST1 have a chromodomain that involved in protein-protein interactions and targeting transcriptional regulators to chromatin.MYST histone acetyltransferase 1 is also involved in ATM function.
Source: Sf9 Cells
Species: Human
Tag: GST
Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Molecular Mass: ~83 kDa
Protein length: 2-467 aa
Purity: >80%
Applications: Western Blot
Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration: 0.1 μg/μ
Gene Name: KAT8 K(lysine) acetyltransferase 8 [ Homo sapiens ]
Official Symbol: KAT8
Synonyms: KAT8; K(lysine) acetyltransferase 8; MYST histone acetyltransferase 1 , MYST1; histone acetyltransferase KAT8; FLJ14040; hMOF; MOF; MYST-1; lysine acetyltransferase 8; histone acetyltransferase MYST1; MYST histone acetyltransferase 1; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; probable histone acetyltransferase MYST1; ortholog of Drosophila males absent on the first (MOF); MYST1;
Gene ID: 84148
mRNA Refseq: NM_032188
Protein Refseq: NP_115564
MIM: 609912
UniProt ID: Q9H7Z6
Chromosome Location: 16p11.1
Pathway: p53 pathway, organism-specific biosystem;
Function: acetyltransferase activity; histone acetyltransferase activity; contributes_to histone acetyltransferase activity (H4-K16 specific); contributes_to histone acetyltransferase activity (H4-K5 specific); contributes_to histone acetyltransferase activity (H4-K8 specific); metal ion binding; methylated histone residue binding; protein binding; transcription factor binding;

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